(Des-Glu22)-Amyloid β-Protein (1-42)

(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-6-amino-1-[[2-[[(2S)-1-[[(2S,3S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxyethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]propanoyl]amino]-5-oxopentanoic acid

Amyloid β-Protein (1-42) Japanese Mutation; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH

White Solid

≥95%

DAEFRHDSGYEVHHQKLVFFADVGSNKGAIIGLMVGGVVIA

Store at -20°C

Soluble in DMSO

InChI=1S/C198H304N54O57S/c1-28-104(20)160(190(301)215-89-146(261)223-127(69-96(4)5)176(287)232-126(64-68-310-27)174(285)245-154(98(8)9)188(299)213-85-143(258)210-86-148(263)244-156(100(12)13)193(304)249-159(103(18)19)194(305)252-161(105(21)29-2)195(306)222-110(26)197(308)309)251-196(307)162(106(22)30-3)250-165(276)107(23)219-144(259)87-211-167(278)120(51-40-42-65-199)227-183(294)136(79-142(203)257)239-187(298)140(92-254)225-147(262)90-214-189(300)155(99(10)11)246-186(297)138(81-153(272)273)233-164(275)109(25)221-175(286)130(71-111-45-34-31-35-46-111)236-179(290)132(73-113-49-38-33-39-50-113)241-191(302)158(102(16)17)248-185(296)128(70-97(6)7)234-169(280)121(52-41-43-66-200)228-171(282)123(58-61-141(202)256)230-180(291)133(75-115-82-206-93-216-115)238-182(293)135(77-117-84-208-95-218-117)242-192(303)157(101(14)15)247-173(284)125(60-63-150(266)267)231-177(288)129(74-114-54-56-118(255)57-55-114)224-145(260)88-212-168(279)139(91-253)243-184(295)137(80-152(270)271)240-181(292)134(76-116-83-207-94-217-116)237-170(281)122(53-44-67-209-198(204)205)229-178(289)131(72-112-47-36-32-37-48-112)235-172(283)124(59-62-149(264)265)226-163(274)108(24)220-166(277)119(201)78-151(268)269/h31-39,45-50,54-57,82-84,93-110,119-140,154-162,253-255H,28-30,40-44,51-53,58-81,85-92,199-201H2,1-27H3,(H2,202,256)(H2,203,257)(H,206,216)(H,207,217)(H,208,218)(H,210,258)(H,211,278)(H,212,279)(H,213,299)(H,214,300)(H,215,301)(H,219,259)(H,220,277)(H,221,286)(H,222,306)(H,223,261)(H,224,260)(H,225,262)(H,226,274)(H,227,294)(H,228,282)(H,229,289)(H,230,291)(H,231,288)(H,232,287)(H,233,275)(H,234,280)(H,235,283)(H,236,290)(H,237,281)(H,238,293)(H,239,298)(H,240,292)(H,241,302)(H,242,303)(H,243,295)(H,244,263)(H,245,285)(H,246,297)(H,247,284)(H,248,296)(H,249,304)(H,250,276)(H,251,307)(H,252,305)(H,264,265)(H,266,267)(H,268,269)(H,270,271)(H,272,273)(H,308,309)(H4,204,205,209)/t104-,105-,106-,107-,108-,109-,110-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,154-,155-,156-,157-,158-,159-,160-,161-,162-/m0/s1

COKXXPRALICHSL-QZFKGIQOSA-N

CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CN=CN3)NC(=O)C(CC4=CN=CN4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC6=CN=CN6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N