Need Assistance?

US & Canada:
+
UK: +

Our Highlights

GMP Grade Efficient workshop for GMP production.
Optimal Prices Buying products on this site guarantees the best price!
Commercial Batches Independent GMP manufacturing suites that handle commercial batches
Prompt Delivery Warehouses in multiple cities to ensure timely delivery
Flexible Quantity Quantities available from milligrams to ton

(Des-Gly10,D-Leu6,D-Leu7,Pro-NHEt9)-LHRH

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

(Des-Gly10,D-Leu6,D-Leu7,Pro-NHEt9)-LHRH is an impurity of Leuprolide, which is a synthetic nonapeptide analog of gonadotropin-releasing hormone used as an antineoplastic agent, a gonadotropin-releasing hormone agonist, and an anti-estrogen.

Category

Others

Catalog number

BAT-015072

CAS number

112710-58-4

Molecular Formula

C59H84N16O12

Molecular Weight

1209.40

(Des-Gly10,D-Leu6,D-Leu7,Pro-NHEt9)-LHRH

Specification

IUPAC Name

(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-(ethylcarbamoyl)pyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

Synonyms

H-Pyr-His-Trp-Ser-Tyr-D-Leu-D-Leu-Arg-Pro-NHEt; 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-D-leucyl-L-arginyl-N-ethyl-L-prolinamide; (D-Leu7)-Leuprorelin; Leuprolide Acetate EP Impurity H; 6-D-Leucine-7-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-luteinizing hormone-releasing factor (pig); L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-D-leucyl-L-arginyl-L-proline ethylamide; D-Leu-Leuprolide; Luteinizing hormone-releasing factor (swine), 6-D-leucine-7-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-

Appearance

White to Off-white Solid

Purity

95%

Density

1.44±0.1 g/cm3

Sequence

Pyr-HWSYllRP-NHEt

Storage

Store at -20°C

Solubility

Soluble in Methanol (Very Slightly), Water (Slightly)

InChI

InChI=1S/C59H84N16O12/c1-6-63-57(86)48-14-10-22-75(48)58(87)41(13-9-21-64-59(60)61)68-51(80)42(23-32(2)3)69-52(81)43(24-33(4)5)70-53(82)44(25-34-15-17-37(77)18-16-34)71-56(85)47(30-76)74-54(83)45(26-35-28-65-39-12-8-7-11-38(35)39)72-55(84)46(27-36-29-62-31-66-36)73-50(79)40-19-20-49(78)67-40/h7-8,11-12,15-18,28-29,31-33,40-48,65,76-77H,6,9-10,13-14,19-27,30H2,1-5H3,(H,62,66)(H,63,86)(H,67,78)(H,68,80)(H,69,81)(H,70,82)(H,71,85)(H,72,84)(H,73,79)(H,74,83)(H4,60,61,64)/t40-,41-,42+,43+,44-,45-,46-,47-,48-/m0/s1

InChI Key

GFIJNRVAKGFPGQ-BPBJJFQZSA-N

Canonical SMILES

CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)NC(=O)C(CC3=CNC4=CC=CC=C43)NC(=O)C(CC5=CN=CN5)NC(=O)C6CCC(=O)N6