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[DOTA-(Bn-pSCN)], pHLIP WT (D) is a derivative of pHLIP-WT, a pH low insertion peptide used as a marker of low pH in tumor allografts and of malignant lesions.
DOTA-(Bn-pSCN)-D-Ala-D-Cys-D-Glu-D-Gln-D-Asn-D-Pro-D-Ile-D-Tyr-D-Trp-D-Ala-D-Arg-D-Tyr-D-Ala-D-Asp-D-Trp-D-Leu-D-Phe-D-Thr-D-Thr-D-Pro-D-Leu-D-Leu-D-Leu-D-Leu-D-Asp-D-Leu-D-Ala-D-Leu-D-Leu-D-Val-D-Asp-D-Ala-D-Asp-D-Glu-D-Gly-D-Thr; DOTA-(Bn-pSCN)-Ala-Cys-Glu-Gln-Asn-Pro-Ile-Tyr-Trp-Ala-Arg-Tyr-Ala-Asp-Trp-Leu-Phe-Thr-Thr-Pro-Leu-Leu-Leu-Leu-Asp-Leu-Ala-Leu-Leu-Val-Asp-Ala-Asp-Glu-Gly-Thr (All D AA)
Appearance
White powder
Sequence
DOTA-(Bn-pSCN)-ACEQNPIYWARYADWLFTTPLLLLDLALLVDADEGT (All D AA)