Fmoc-3-benzothienyl-D-alanine
Need Assistance?
  • US & Canada:
    +
  • UK: +

Fmoc-3-benzothienyl-D-alanine

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Category
Fmoc-Amino Acids
Catalog number
BAT-007346
CAS number
177966-61-9
Molecular Formula
C26H21NO4S
Molecular Weight
443.51
Fmoc-3-benzothienyl-D-alanine
IUPAC Name
(2R)-3-(1-benzothiophen-3-yl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
Synonyms
Fmoc-3-D-Ala(3-benzothienyl)-OH
Related CAS
177966-60-8 (L-isomer)
Appearance
White to off-white powder
Purity
≥ 99.5% (Chiral HPLC)
Density
1.356 g/cm3
Boiling Point
690.8°C at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C26H21NO4S/c28-25(29)23(13-16-15-32-24-12-6-5-7-17(16)24)27-26(30)31-14-22-20-10-3-1-8-18(20)19-9-2-4-11-21(19)22/h1-12,15,22-23H,13-14H2,(H,27,30)(H,28,29)/t23-/m1/s1
InChI Key
BQIZNDWONIMCGM-HSZRJFAPSA-N
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CSC5=CC=CC=C54)C(=O)O

Fmoc-3-benzothienyl-D-alanine, a synthetic amino acid derivative pivotal in peptide synthesis and biochemical research, showcases a multitude of applications across various domains. Here are the key applications of Fmoc-3-benzothienyl-D-alanine, presented with high perplexity and burstiness:

Peptide Synthesis: Foundational in solid-phase peptide synthesis, Fmoc-3-benzothienyl-D-alanine bestows distinct properties upon resulting peptides, potentially enhancing their stability and biological activity. This specialized amino acid empowers researchers to sculpt tailored peptides for investigative and therapeutic purposes, fostering a personalized approach to peptide design and production.

Structure-Activity Relationship (SAR) Studies: Bridging peptide research and functional exploration, scientists leverage Fmoc-3-benzothienyl-D-alanine in SAR studies to delve into the intricate interplay between peptide structures and biological functions. By strategically incorporating this derivative into peptide sequences, researchers meticulously analyze how specific modifications impact molecular interactions and efficacy, fueling optimization endeavors for peptide-based drugs and deepening insights into their modes of action.

Drug Design and Development: Spearheading pharmaceutical innovation, Fmoc-3-benzothienyl-D-alanine plays a pivotal role in enhancing the pharmacokinetic and pharmacodynamic properties of peptide-based drug candidates. Through integration of this modification, peptides gain enhanced stability, membrane permeability, and target specificity, fortifying the development of potent and selective therapeutic peptides poised to address unmet clinical exigencies.

Biochemical Assays: Within the realm of biochemical research, Fmoc-3-benzothienyl-D-alanine serves as a versatile instrument for studying enzyme-substrate interactions and peptide-receptor binding phenomena. Its unique chemical composition facilitates labeling peptides with fluorescent or affinity tags, enabling visualization and quantification of binding events in biochemical assays. This critical application aids in unraveling complex biochemical pathways, illuminating potential drug targets, and enriching comprehension of intricate biological processes.

Online Inquiry
Verification code
Inquiry Basket