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Fmoc-Glu(Cys(Fmoc)-Gly-OH)-OH

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

N,S-Bis-Fmoc-glutathione is a very potent inhibitor of mammalian glyoxalase II (Ki = 0.08 µM for glyoxalase II purified from calf liver).

Category

Peptide Inhibitors

Catalog number

BAT-015972

CAS number

149438-56-2

Molecular Formula

C40H37N3O10S

Molecular Weight

751.80

Specification

IUPAC Name

(2S)-5-[[(2R)-1-(carboxymethylamino)-3-(9H-fluoren-9-ylmethoxycarbonylsulfanyl)-1-oxopropan-2-yl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoic acid

Synonyms

N,S-Bis-Fmoc-glutathione

Density

1.392 g/cm3

Sequence

Fmoc-gGlu-Cys(Fmoc)-Gly-OH

Storage

Store at -20°C

InChI

InChI=1S/C40H37N3O10S/c44-35(18-17-33(38(48)49)43-39(50)52-20-31-27-13-5-1-9-23(27)24-10-2-6-14-28(24)31)42-34(37(47)41-19-36(45)46)22-54-40(51)53-21-32-29-15-7-3-11-25(29)26-12-4-8-16-30(26)32/h1-16,31-34H,17-22H2,(H,41,47)(H,42,44)(H,43,50)(H,45,46)(H,48,49)/t33-,34-/m0/s1

InChI Key

RMCMELVMNFUWTF-HEVIKAOCSA-N

Canonical SMILES

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CCC(=O)NC(CSC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46)C(=O)NCC(=O)O)C(=O)O