Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH
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Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH

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Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH is a yellowish medical intermediate in the synthesis of Tirzepatide. Tirzepatide is a dual GIP and GLP-1 receptor agonist and a drug candidate for the treatment of type 2 diabetes.

Category
Peptide Synthesis Reagents
Catalog number
BAT-016679
CAS number
2460751-66-8
Molecular Formula
C66H105N5O16
Molecular Weight
1224.59
Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH
Size Price Stock Quantity
1 g $398 In stock
IUPAC Name
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[[2-[2-[2-[[2-[2-[2-[[(4R)-5-[(2-methylpropan-2-yl)oxy]-4-[[20-[(2-methylpropan-2-yl)oxy]-20-oxoicosanoyl]amino]-5-oxopentanoyl]amino]ethoxy]ethoxy]acetyl]amino]ethoxy]ethoxy]acetyl]amino]hexanoic acid
Synonyms
Fmoc-Lys(tBuO-Ara-Glu(AEEA-AEEA)-OtBu)-OH
Purity
98%
Density
1.121±0.06 g/cm3 (Predicted)
Boiling Point
1225.0±65.0 °C (Predicted)
InChI
InChI=1S/C66H105N5O16/c1-65(2,3)86-61(76)35-22-20-18-16-14-12-10-8-7-9-11-13-15-17-19-21-34-58(73)70-56(63(79)87-66(4,5)6)36-37-57(72)68-39-41-81-43-46-84-49-60(75)69-40-42-82-44-45-83-48-59(74)67-38-28-27-33-55(62(77)78)71-64(80)85-47-54-52-31-25-23-29-50(52)51-30-24-26-32-53(51)54/h23-26,29-32,54-56H,7-22,27-28,33-49H2,1-6H3,(H,67,74)(H,68,72)(H,69,75)(H,70,73)(H,71,80)(H,77,78)/t55-,56+/m0/s1
InChI Key
YWLOWAZATOAHDO-KKQLDWOFSA-N
Canonical SMILES
CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NCCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13)C(=O)OC(C)(C)C
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