Fmoc-L-serine (BAT-003845)
* For research use only

N-Fmoc-L-serine is an N-Fmoc-protected form of L-Serine. L-Serine is a non-essential amino acid that is required for the synthesis of sphingolipids and phosphatidylserine, compounds that are important for central nervous system neuronal survival. L-Serine is also important in intermediary metabolism in eukaryotic cells.

Category
Fmoc-Amino Acids
Catalog number
BAT-003845
CAS number
73724-45-5
Molecular Formula
C18H17NO5
Molecular Weight
327.30
Fmoc-L-serine
Synonyms
Fmoc-L-Ser-OH; Fmoc-L-β-hydroxyalanine(S)-Fmoc-2-amino-3-hydroxypropionic acid; FMOC-SER-OH; N-Fmoc-L-serine-OH; N-FMOC-L-SERINE; FMOC-SERINE; FMOC-SER
Appearance
White powder
Purity
≥ 99.5% (Chiral HPLC)
Density
1.362±0.06 g/cm3
Melting Point
~ 95 °C
Boiling Point
599.3±50.0 °C
Storage
Store at RT
1.Practical synthesis of the 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-beta-D-glucosides of Fmoc-serine and Fmoc-threonine and their benzyl esters.
Carvalho I1, Scheuerl SL, Ravindranathan Kartha KP, Field RA. Carbohydr Res. 2003 May 1;338(10):1039-43.
Mercuric bromide-promoted glycosylation of Fmoc-Ser-OBn and Fmoc-Thr-OBn with 2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-alpha-D-glucopyranosyl chloride in refluxing 1,2-dichloroethane gave the corresponding beta-glycosides in good yields (64 and 62%, respectively). Direct coupling of the commercially available Fmoc-Ser-OH and Fmoc-Thr-OH carboxylic acids under similar conditions gave the corresponding beta-glycosides, possessing free carboxyl groups, in moderate yields (50 and 40%, respectively).
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L

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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