Need Assistance?

US & Canada:
+
UK: +

FAQs

Resources

Our Highlights

GMP Grade Efficient workshop for GMP production.
Optimal Prices Buying products on this site guarantees the best price!
Commercial Batches Independent GMP manufacturing suites that handle commercial batches
Prompt Delivery Warehouses in multiple cities to ensure timely delivery
Flexible Quantity Quantities available from milligrams to ton

Application Area

Fmoc-PNA-D(tetraBoc)-OH

Name: Fmoc-PNA-D(tetraBoc)-OH
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Fmoc-PNA-D(tetraBoc)-OH is a peptide nucleic acid (PNA) monomer used in the synthesis of PNA oligomers. It features an Fmoc (9-fluorenylmethyloxycarbonyl) protecting group on the terminal amine and tetraBoc (tetra tert-butoxycarbonyl) protecting groups on the modified base D. These protecting groups help maintain the integrity of the monomer during the solid-phase synthesis process, allowing for precise and controlled assembly of PNA sequences. This monomer is valuable for creating PNAs with tailored binding characteristics and increased stability for various biochemical applications.

Category

Fmoc PNA Monomers

Catalog number

BAT-014349

CAS number

2101661-88-3

Molecular Formula

C46H58N8O13

Molecular Weight

931.00

Specification

IUPAC Name

2-[[2-[2,6-bis[bis[(2-methylpropan-2-yl)oxycarbonyl]amino]purin-9-yl]acetyl]-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]amino]acetic acid

Synonyms

2-(N-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-2-(2,6-bis(bis(tert-butoxycarbonyl)amino)-9H-purin-9-yl)acetamido)acetic acid; N-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)ethyl)-N-(2-(2,6-bis(bis(tert-butoxycarbonyl)amino)-9H-purin-9-yl)acetyl)glycine; 2-{2-[2,6-bis({bis[(tert-butoxy)carbonyl]amino})-9H-purin-9-yl]-N-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]acetamido}acetic acid

Appearance

White to Light Beige Solid

Purity

≥95%

Density

1.30±0.1 g/cm3

Melting Point

135-140°C

Boiling Point

402.2±55.0°C (Predicted)

Storage

Store at -20°C under inert atmosphere

Solubility

Soluble in DMSO (Slightly), Methanol (Slightly)

InChI

InChI=1S/C46H58N8O13/c1-43(2,3)64-39(59)53(40(60)65-44(4,5)6)36-34-35(49-37(50-36)54(41(61)66-45(7,8)9)42(62)67-46(10,11)12)52(26-48-34)23-32(55)51(24-33(56)57)22-21-47-38(58)63-25-31-29-19-15-13-17-27(29)28-18-14-16-20-30(28)31/h13-20,26,31H,21-25H2,1-12H3,(H,47,58)(H,56,57)

InChI Key

FNWBHNGZUCVYGL-UHFFFAOYSA-N

Canonical SMILES

CC(C)(C)OC(=O)N(C1=NC(=NC2=C1N=CN2CC(=O)N(CCNC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35)CC(=O)O)N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

GIP (human)

CAT NO. : BAT-006165