Formyl-L-alanine
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Formyl-L-alanine

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Category
L-Amino Acids
Catalog number
BAT-003939
CAS number
10512-86-4
Molecular Formula
C4H7NO3
Molecular Weight
117.10
Formyl-L-alanine
IUPAC Name
(2S)-2-formamidopropanoic acid
Synonyms
For-L-Ala-OH; formylalanine; FOR-ALA-OH; FORMYL-L-ALANINE; N-Formyl-L-alanine
Appearance
White powder
Purity
≥ 99% (HPLC)
Density
1.223±0.06 g/cm3
Melting Point
124-140 °C
Boiling Point
83-86 °C
Storage
Store at 2-8 °C
InChI
InChI=1S/C4H7NO3/c1-3(4(7)8)5-2-6/h2-3H,1H3,(H,5,6)(H,7,8)/t3-/m0/s1
InChI Key
SRBATDDRZARFDZ-VKHMYHEASA-N
Canonical SMILES
CC(C(=O)O)NC=O

Formyl-L-alanine, a versatile modified amino acid, finds diverse applications in biochemistry and biotechnology. Here are the key applications presented with high perplexity and burstiness:

Peptide Synthesis: Serving a crucial role in peptide and protein synthesis, Formyl-L-alanine is instrumental in incorporating formyl groups at specific sites, enhancing the diversity of peptides for various biochemical studies. The selective removal of the formyl group under mild conditions allows for meticulous control in peptide assembly, enabling precise manipulation of peptide structures for targeted research purposes.

Chemical Biology: In the intricate field of chemical biology, Formyl-L-alanine is a pivotal tool for studying protein-ligand interactions and enzyme mechanisms. By integrating Formyl-L-alanine into proteins, scientists can create specialized probes to explore active sites and protein dynamics, shedding light on the intricate structure-function relationships within complex biological systems through meticulous and detailed experimentation.

Pharmaceutical Development: Positioned at the forefront of pharmaceutical innovation, Formyl-L-alanine plays a crucial role in designing and synthesizing novel therapeutic agents. Acting as a foundational building block for peptide-based drugs, Formyl-L-alanine enhances the stability and bioactivity of these agents, paving the way for the development of cutting-edge treatments targeting various diseases such as cancer and infectious diseases through intricate and precise molecular modifications.

Bioconjugation: In the realm of bioconjugation techniques, Formyl-L-alanine emerges as a key component for linking bioactive molecules to proteins and other biomolecules. This integration enables the in-depth study of protein function, localization, and interactions within live cells, offering valuable insights into biological processes at a molecular level. Bioconjugates featuring Formyl-L-alanine serve as indispensable tools in both research and clinical diagnostics, providing a platform for exploring the intricate connections between biomolecules with a high degree of complexity and variability.

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