GALA, Pore-Forming Peptide

(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-indol-3-yl)propanoyl]amino]-4-carboxybutanoyl]amino]propanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-carboxy-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-carboxy-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-carboxy-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-carboxy-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-carboxy-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxyethyl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

pore-forming peptide GALA; H-Trp-Glu-Ala-Ala-Leu-Ala-Glu-Ala-Leu-Ala-Glu-Ala-Leu-Ala-Glu-His-Leu-Ala-Glu-Ala-Leu-Ala-Glu-Ala-Leu-Glu-Ala-Leu-Ala-Ala-OH; L-tryptophyl-L-alpha-glutamyl-L-alanyl-L-alanyl-L-leucyl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-alanyl-L-alpha-glutamyl-L-histidyl-L-leucyl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-alanyl-L-leucyl-L-alanyl-L-alanine

White powder

WEAALAEALAEALAEHLAEALAEALEALAA

Store at -20 °C

InChI=1S/C136H215N33O45/c1-59(2)47-92(128(205)148-67(16)108(185)154-79(28)136(213)214)163-118(195)77(26)147-126(203)90(38-45-105(180)181)161-134(211)98(53-65(13)14)167-119(196)78(27)146-124(201)88(36-43-103(176)177)157-111(188)71(20)151-131(208)95(50-62(7)8)165-116(193)75(24)145-123(200)87(35-42-102(174)175)158-112(189)72(21)153-133(210)97(52-64(11)12)168-135(212)99(55-81-57-138-58-140-81)169-127(204)91(39-46-106(182)183)159-113(190)73(22)152-132(209)96(51-63(9)10)166-117(194)76(25)144-122(199)86(34-41-101(172)173)156-110(187)70(19)150-130(207)94(49-61(5)6)164-115(192)74(23)143-121(198)85(33-40-100(170)171)155-109(186)69(18)149-129(206)93(48-60(3)4)162-114(191)68(17)141-107(184)66(15)142-125(202)89(37-44-104(178)179)160-120(197)83(137)54-80-56-139-84-32-30-29-31-82(80)84/h29-32,56-79,83,85-99,139H,33-55,137H2,1-28H3,(H,138,140)(H,141,184)(H,142,202)(H,143,198)(H,144,199)(H,145,200)(H,146,201)(H,147,203)(H,148,205)(H,149,206)(H,150,207)(H,151,208)(H,152,209)(H,153,210)(H,154,185)(H,155,186)(H,156,187)(H,157,188)(H,158,189)(H,159,190)(H,160,197)(H,161,211)(H,162,191)(H,163,195)(H,164,192)(H,165,193)(H,166,194)(H,167,196)(H,168,212)(H,169,204)(H,170,171)(H,172,173)(H,174,175)(H,176,177)(H,178,179)(H,180,181)(H,182,183)(H,213,214)/t66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,83-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-/m0/s1

RQKQIWHKTICUJB-YJPINGMISA-N

C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)N