Gap 26 (BAT-006105)
* For research use only

Gap 26 is a gap junction blocker which is corresponding to residues 63 - 75 of connexin 43. Gap 26 was shown to attenuate rhythmic contractile activity of rabbit arterial smooth muscle (IC50 = 28.4 μM). It also inhibits IP3-induced ATP release but does not inhibit gap junctional coupling in endothelial cells.

Category
Peptide Inhibitors
Catalog number
BAT-006105
CAS number
197250-15-0
Molecular Formula
C70H107N19O19S
Molecular Weight
1550.79
Gap 26
Ordering Information
Catalog Number Size Price Stock Quantity
BAT-006105 10 mg $228 In stock
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Synonyms
Gap 26; Gap26; Gap-26
Purity
98%
Sequence
VCYDKSFPISHVR
InChI
InChI=1S/C70H107N19O19S/c1-7-38(6)56(67(105)85-50(33-91)61(99)81-46(29-41-31-75-35-77-41)60(98)87-55(37(4)5)66(104)79-44(69(107)108)18-13-25-76-70(73)74)88-64(102)52-19-14-26-89(52)68(106)48(28-39-15-9-8-10-16-39)83-62(100)49(32-90)84-57(95)43(17-11-12-24-71)78-59(97)47(30-53(93)94)82-58(96)45(27-40-20-22-42(92)23-21-40)80-63(101)51(34-109)86-65(103)54(72)36(2)3/h8-10,15-16,20-23,31,35-38,43-52,54-56,90-92,109H,7,11-14,17-19,24-30,32-34,71-72H2,1-6H3,(H,75,77)(H,78,97)(H,79,104)(H,80,101)(H,81,99)(H,82,96)(H,83,100)(H,84,95)(H,85,105)(H,86,103)(H,87,98)(H,88,102)(H,93,94)(H,107,108)(H4,73,74,76)/t38-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,54-,55-,56-/m0/s1
InChI Key
FDPIMWZHGJNESB-VCSXYVMHSA-N
Canonical SMILES
CCC(C)C(C(=O)NC(CO)C(=O)NC(CC1=CN=CN1)C(=O)NC(C(C)C)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C2CCCN2C(=O)C(CC3=CC=CC=C3)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CC(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(CS)NC(=O)C(C(C)C)N
Bio Calculators
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Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
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