(Gly21)-Amyloid β-Protein (1-42)

(4S)-4-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]propanoyl]amino]-4-carboxybutanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-oxopentanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-5-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-6-amino-1-[[2-[[(2S)-1-[[(2S,3S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(1S)-1-carboxyethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid

Amyloid β-Protein (1-42) A21G; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Gly-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-alpha-aspartyl-L-seryl-glycyl-L-tyrosyl-L-alpha-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-glycyl-L-alpha-glutamyl-L-alpha-aspartyl-L-valyl-glycyl-L-seryl-L-asparagyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-isoleucyl-glycyl-L-leucyl-L-methionyl-L-valyl-glycyl-glycyl-L-valyl-L-valyl-L-isoleucyl-L-alanine

White Powder

≥95% by HPLC

DAEFRHDSGYEVHHQKLVFFGEDVGSNKGAIIGLMVGGVVIA

Store at -20°C

Soluble in DMSO

InChI=1S/C202H309N55O60S/c1-27-106(20)164(194(309)220-91-149(267)228-129(70-98(4)5)180(295)237-128(65-69-318-26)179(294)250-158(100(8)9)192(307)218-86-145(263)214-87-151(269)249-160(102(12)13)197(312)254-163(105(18)19)198(313)257-165(107(21)28-2)199(314)226-111(25)201(316)317)256-200(315)166(108(22)29-3)255-168(283)109(23)224-146(264)88-215-170(285)121(50-39-41-66-203)232-187(302)138(80-144(207)262)243-191(306)142(94-259)230-150(268)92-219-193(308)159(101(10)11)251-190(305)140(82-157(280)281)244-175(290)124(58-62-152(270)271)227-147(265)89-216-171(286)131(72-112-44-33-30-34-45-112)239-183(298)134(74-114-48-37-32-38-49-114)246-195(310)162(104(16)17)253-189(304)130(71-99(6)7)238-173(288)122(51-40-42-67-204)233-176(291)125(57-61-143(206)261)235-184(299)135(76-116-83-210-95-221-116)242-186(301)137(78-118-85-212-97-223-118)247-196(311)161(103(14)15)252-178(293)127(60-64-154(274)275)236-181(296)132(75-115-53-55-119(260)56-54-115)229-148(266)90-217-172(287)141(93-258)248-188(303)139(81-156(278)279)245-185(300)136(77-117-84-211-96-222-117)241-174(289)123(52-43-68-213-202(208)209)234-182(297)133(73-113-46-35-31-36-47-113)240-177(292)126(59-63-153(272)273)231-167(282)110(24)225-169(284)120(205)79-155(276)277/h30-38,44-49,53-56,83-85,95-111,120-142,158-166,258-260H,27-29,39-43,50-52,57-82,86-94,203-205H2,1-26H3,(H2,206,261)(H2,207,262)(H,210,221)(H,211,222)(H,212,223)(H,214,263)(H,215,285)(H,216,286)(H,217,287)(H,218,307)(H,219,308)(H,220,309)(H,224,264)(H,225,284)(H,226,314)(H,227,265)(H,228,267)(H,229,266)(H,230,268)(H,231,282)(H,232,302)(H,233,291)(H,234,297)(H,235,299)(H,236,296)(H,237,295)(H,238,288)(H,239,298)(H,240,292)(H,241,289)(H,242,301)(H,243,306)(H,244,290)(H,245,300)(H,246,310)(H,247,311)(H,248,303)(H,249,269)(H,250,294)(H,251,305)(H,252,293)(H,253,304)(H,254,312)(H,255,283)(H,256,315)(H,257,313)(H,270,271)(H,272,273)(H,274,275)(H,276,277)(H,278,279)(H,280,281)(H,316,317)(H4,208,209,213)/t106-,107-,108-,109-,110-,111-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,158-,159-,160-,161-,162-,163-,164-,165-,166-/m0/s1

BJWOJWXWGWYBRL-SLSHUNJASA-N

CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)NC(C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CN=CN3)NC(=O)C(CC4=CN=CN4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC6=CN=CN6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N