GRGDSP acetate
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GRGDSP acetate

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GRGDSP acetate, a synthetic linear RGD peptide, is an integrin inhibitor that can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization.

Category
Peptide Inhibitors
Catalog number
BAT-016356
Molecular Formula
C24H41N9O12
Molecular Weight
647.64
GRGDSP acetate
IUPAC Name
acetic acid;(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carboxylic acid
Synonyms
H-Gly-Arg-Gly-Asp-Ser-Pro-OH.CH3CO2H; Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline acetic acid; L-Proline, 1-[N-[N-[N-(N2-glycyl-L-arginyl)glycyl]-L-α-aspartyl]-L-seryl]-, acetate
Related CAS
91037-75-1 (free base)
Purity
≥95%
Sequence
GRGDSP.CH3CO2H
Storage
Store at -20°C
Solubility
Soluble in Water
InChI
InChI=1S/C22H37N9O10.C2H4O2/c23-8-15(33)28-11(3-1-5-26-22(24)25)18(37)27-9-16(34)29-12(7-17(35)36)19(38)30-13(10-32)20(39)31-6-2-4-14(31)21(40)41;1-2(3)4/h11-14,32H,1-10,23H2,(H,27,37)(H,28,33)(H,29,34)(H,30,38)(H,35,36)(H,40,41)(H4,24,25,26);1H3,(H,3,4)/t11-,12-,13-,14-;/m0./s1
InChI Key
KXZCJOGLGCWKBQ-ZMNOQRQPSA-N
Canonical SMILES
CC(=O)O.C1CC(N(C1)C(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(CCCN=C(N)N)NC(=O)CN)C(=O)O
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