H-β-(2-Furyl)-D-alanine
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H-β-(2-Furyl)-D-alanine

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Category
D-Amino Acids
Catalog number
BAT-005553
CAS number
110772-46-8
Molecular Formula
C7H9NO3
Molecular Weight
155.16
H-β-(2-Furyl)-D-alanine
IUPAC Name
(2R)-2-amino-3-(furan-2-yl)propanoic acid
Synonyms
(R)-2-Amino-3-(furan-2-yl)propanoicacid; 110772-46-8; D-2-Furylalanine; 3-(2-Furyl)-D-alanine; (2R)-2-amino-3-(furan-2-yl)propanoicacid; D-3-(2-Furyl)-alanine
Appearance
Off-white solid
Purity
≥ 98%
Density
1.290±0.06 g/cm3
Boiling Point
284.1±30.0 °C
Storage
Store at 2-8°C
InChI
InChI=1S/C7H9NO3/c8-6(7(9)10)4-5-2-1-3-11-5/h1-3,6H,4,8H2,(H,9,10)/t6-/m1/s1
InChI Key
RXZQHZDTHUUJQJ-ZCFIWIBFSA-N
Canonical SMILES
C1=COC(=C1)CC(C(=O)O)N

H-β-(2-Furyl)-D-alanine, a non-standard amino acid with diverse applications in bioscience, is utilized in various innovative ways. Here are the key applications depicted with a high degree of perplexity and burstiness:

Peptide Synthesis: Incorporating H-β-(2-Furyl)-D-alanine into synthetic peptides enables researchers to explore their structural nuances and biological functionalities. By introducing functional modifications, peptides can gain specific binding affinities or enzymatic stability, shedding light on peptide-protein interactions and facilitating peptide-based drug design endeavors.

Enzyme Inhibition Studies: Employing this compound as a versatile tool, scientists delve into enzyme mechanisms by leveraging its role as a substrate mimic or inhibitor. By interacting with the active sites of specific enzymes, it unravels catalytic processes and enzyme specificity, paving the way for developing novel inhibitors with therapeutic potential.

Protein Engineering: Within the realm of protein engineering, H-β-(2-Furyl)-D-alanine plays a pivotal role in crafting proteins with unique properties or heightened stability. Its incorporation induces conformational changes that enhance protein function or bolster resistance to denaturation, thus aiding in the optimization of industrial enzymes and therapeutic proteins for enhanced performance.

Drug Design and Development: In the realm of drug discovery, H-β-(2-Furyl)-D-alanine serves as a cornerstone for designing and synthesizing novel pharmacophores. Its distinctive chemical structure allows for the creation of compounds with promising therapeutic benefits, prompting researchers to explore these compounds for the development of next-generation drugs with improved efficacy and selectivity.

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