1.Resolving Nonadiabatic Dynamics of Hydrated Electrons Using Ultrafast Photoemission Anisotropy.
Karashima S1, Yamamoto Y1, Suzuki T1. Phys Rev Lett. 2016 Apr 1;116(13):137601. doi: 10.1103/PhysRevLett.116.137601. Epub 2016 Apr 1.
We have studied ultrafast nonadiabatic dynamics of excess electrons trapped in the band gap of liquid water using time- and angle-resolved photoemission spectroscopy. Anisotropic photoemission from the first excited state was discovered, which enabled unambiguous identification of nonadiabatic transition to the ground state in 60 fs in H_{2}O and 100 fs in D_{2}O. The photoelectron kinetic energy distribution exhibited a rapid spectral shift in ca. 20 fs, which is ascribed to the librational response of a hydration shell to electronic excitation. Photoemission anisotropy indicates that the electron orbital in the excited state is depolarized in less than 40 fs.
2.Bioactive α-pyrone meroterpenoids from mangrove endophytic fungus Penicillium sp.
Ding B1,2, Wang Z2, Huang X1, Liu Y1, Chen W2, She Z1. Nat Prod Res. 2016 Apr 11:1-8. [Epub ahead of print]
Five α-pyrone meroterpenoids, including one new 3-epiarigsugacin E (1) and four known compounds, arisugacin D (2), arisugacin B (3), territrem C (4) and terreulactone C (5) were obtained from the marine fungus Penicillium sp. SK5GW1L. Their structures were identified by MS and NMR experiments, and the absolute configuration of compound 1 was further confirmed by low temperature (150 K) single crystal X-ray diffraction with Cu Kα radiation. Compounds 3, 4 and 5 showed strong inhibitory activities against acetylcholinesterase (AchE) with IC50 values of 3.03, 0.23 and 0.028 μM, respectively.
3.Calcium-Vitamin D Co-supplementation Affects Metabolic Profiles, but not Pregnancy Outcomes, in Healthy Pregnant Women.
Asemi Z1, Samimi M2, Siavashani MA3, Mazloomi M4, Tabassi Z2, Karamali M4, Jamilian M5, Esmaillzadeh A6. Int J Prev Med. 2016 Mar 1;7:49. doi: 10.4103/2008-7802.177895. eCollection 2016.
BACKGROUND: Pregnancy is associated with unfavorable metabolic profile, which might in turn result in adverse pregnancy outcomes. The current study was designed to evaluate the effects of calcium plus Vitamin D administration on metabolic status and pregnancy outcomes in healthy pregnant women.
4.Investigating the roles of core and local temperature on forearm skin blood flow.
Mallette MM1, Hodges GJ1, McGarr GW1, Gabriel DA2, Cheung SS3. Microvasc Res. 2016 Apr 9. pii: S0026-2862(16)30024-3. doi: 10.1016/j.mvr.2016.03.010. [Epub ahead of print]
We sought to isolate the contributions of core and local temperature on forearm skin blood flow (SkBF), and to examine the interaction between local- and reflexive-mechanisms of SkBF control. Forearm SkBF was assessed using laser-Doppler flowmetry in eight males and eight females during normothermia and hyperthermia (+1.2°C rectal temperature). Mean experimental forearm temperature was manipulated in four, 5min blocks between neutral (A: 33.0°C) and warm (B: 38.5°C) in an A-B-A-B fashion during normothermia, and B-A-B-A during hyperthermia. Mean control forearm skin temperature was maintained at ~33°C. Finally, local heating to 44°C was performed on both forearms to elicit maximal SkBF. Data are presented as a percentage of maximal cutaneous vascular conductance (CVC), calculated as laser-Doppler flux divided by mean arterial pressure. No sex differences were observed in any CVC measures (P>0.05). During normothermia, increasing experimental forearm temperature to 38.
