H-Gly-Pro-Gly-NH2
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H-Gly-Pro-Gly-NH2

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H-Gly-Pro-Gly-NH2 inhibits HIV-1 replication through its metabolite α-hydroxyglycineamide. It increases the antiviral activity of zidovudine and ritonavir.

Category
Functional Peptides
Catalog number
BAT-014482
CAS number
141497-12-3
Molecular Formula
C9H16N4O3
Molecular Weight
228.25
H-Gly-Pro-Gly-NH2
IUPAC Name
(2S)-1-(2-aminoacetyl)-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide
Synonyms
GPG-NH2; glycyl-L-prolyl-glycinamide; Glycinamide, glycyl-L-prolyl-; Glycyl-prolyl-glycyl amide; (2S)-1-(2-amino-1-oxoethyl)-N-(2-amino-2-oxoethyl)-2-pyrrolidinecarboxamide
Related CAS
352284-14-1 (monohydrochloride)
Appearance
White Powder
Purity
≥95% by HPLC
Density
1.326±0.06 g/cm3 (Predicted)
Boiling Point
618.0±55.0°C (Predicted)
Sequence
Gly-Pro-Gly-NH2
Storage
Store at -20°C
Solubility
Soluble in Methanol
InChI
InChI=1S/C9H16N4O3/c10-4-8(15)13-3-1-2-6(13)9(16)12-5-7(11)14/h6H,1-5,10H2,(H2,11,14)(H,12,16)/t6-/m0/s1
InChI Key
JWWLMJFURJYNEX-LURJTMIESA-N
Canonical SMILES
C1CC(N(C1)C(=O)CN)C(=O)NCC(=O)N
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