Inquiry Basket
H-Ile-Aib-Leu-OMe is a protected tripeptide used in peptide synthesis. The H indicates a free N-terminus on the isoleucine (Ile) residue, allowing for further peptide coupling or reactions. Aib (α-aminoisobutyric acid), known for inducing helical structures, follows isoleucine. Leu (Leucine), the last amino acid in the sequence, adds hydrophobic characteristics. The OMe (methyl ester) at the C-terminus shows that the carboxyl group of leucine is esterified, which can be advantageous for controlling reactivity or facilitating further modifications. This peptide is used to incorporate isoleucine, Aib, and leucine into peptides, with specific protection of functional groups to ensure controlled synthesis.
