H-Pro-NH2
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H-Pro-NH2

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An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4.

Category
Cyclic Amino Acids
Catalog number
BAT-003438
CAS number
7531-52-4
Molecular Formula
C5H10N2O
Molecular Weight
114.10
H-Pro-NH2
IUPAC Name
(2S)-pyrrolidine-2-carboxamide
Synonyms
L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide
Appearance
Off-white to Pale Yellow Solid
Purity
≥95%
Density
1.106±0.06 g/cm3
Melting Point
93°C
Boiling Point
303.6±31.0°C at 760 mmHg
Storage
Store at 2-8°C
Solubility
Soluble in Chloroform (Slightly), Methanol (Slightly)
InChI
InChI=1S/C5H10N2O/c6-5(8)4-2-1-3-7-4/h4,7H,1-3H2,(H2,6,8)/t4-/m0/s1
InChI Key
VLJNHYLEOZPXFW-BYPYZUCNSA-N
Canonical SMILES
C1CC(NC1)C(=O)N
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