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H-TYR-TYR-OH

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Tyr-Tyr and Tyr-Tyr-Tyr efficiently inhibit angiotensin I-converting enzyme (ACE) from rabbit lung, their IC50 values were 34 μM and 51 μM, respectively. These two tyrosine peptides exhibited a mix of competitive and noncompetitive inhibitions.

Category

Peptide Inhibitors

Catalog number

BAT-015892

CAS number

1050-28-8

Molecular Formula

C18H20N2O5

Molecular Weight

344.36

Specification

IUPAC Name

(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid

Synonyms

Tyr-tyr; Tyrosyltyrosine; L-Tyrosyl-L-tyrosine; Peptide tyrosine-tyrosine; L-Tyr-L-Tyr; N-L-tyrosyl-L-tyrosine

Purity

95%

Sequence

H-Tyr-Tyr-OH

InChI

InChI=1S/C18H20N2O5/c19-15(9-11-1-5-13(21)6-2-11)17(23)20-16(18(24)25)10-12-3-7-14(22)8-4-12/h1-8,15-16,21-22H,9-10,19H2,(H,20,23)(H,24,25)/t15-,16-/m0/s1

InChI Key

JAQGKXUEKGKTKX-HOTGVXAUSA-N

Canonical SMILES

C1=CC(=CC=C1CC(C(=O)NC(CC2=CC=C(C=C2)O)C(=O)O)N)O