Peptide

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Application Area

IL-6 (88-121) (human)

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IL-6 (88-121) competitively inhibits the binding of human IL-6 to its receptor by interacting with the IL-6 receptor to a significant degree.

Category

Peptide Inhibitors

Catalog number

BAT-015925

CAS number

145990-81-4

Molecular Formula

C179H281N45O58S

Molecular Weight

4023.47

Specification

IUPAC Name

2-(4-methoxyphenyl)-4-methyl-5,5-diphenylpyrazolidin-3-one

Synonyms

H-ILE-ILE-THR-GLY-LEU-LEU-GLU-PHE-GLU-VAL-TYR-LEU-GLU-TYR-LEU-GLN-ASN-ARG-PHE-GLU-SER-SER-GLU-GLU-GLN-ALA-ARG-ALA-VAL-GLN-MET-SER-THR-LYS-OH; interleukin-6 fragment 88-121

Purity

95%

Sequence

IITGLLEFEVYLEYLQNRFESSEEQARAVQMSTK

InChI

InChI=1S/C23H22N2O2/c1-17-22(26)25(20-13-15-21(27-2)16-14-20)24-23(17,18-9-5-3-6-10-18)19-11-7-4-8-12-19/h3-17,24H,1-2H3

InChI Key

IGVATZBOONVYEJ-UHFFFAOYSA-N

Canonical SMILES

CC1C(=O)N(NC1(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=C(C=C4)OC