L-Alanine amide hydrochloride
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L-Alanine amide hydrochloride

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L-Alanine Amide is used for preparation of novel amide derivatives of steroidal[3,2-c]pyrazole compounds with glucocorticoid activity.

Category
L-Amino Acids
Catalog number
BAT-003950
CAS number
33208-99-0
Molecular Formula
C3H8N2O·HCl
Molecular Weight
124.60
L-Alanine amide hydrochloride
IUPAC Name
(2S)-2-aminopropanamide;hydrochloride
Synonyms
L-Ala-NH2 HCl; Ala-NH2 HCl; H-Ala-NH2 HCl; L-Alanamine Hydrochloride; L-Alaninamide Hydrochloride; (S)-2-Aminopropanamide hydrochloride
Appearance
White crystals or crystalline powder
Purity
≥ 98% (HPLC)
Melting Point
210-220 °C
Boiling Point
247.4 °C at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C3H8N2O.ClH/c1-2(4)3(5)6;/h2H,4H2,1H3,(H2,5,6);1H/t2-;/m0./s1
InChI Key
FIAINKIUSZGVGX-DKWTVANSSA-N
Canonical SMILES
CC(C(=O)N)N.Cl

L-Alanine amide hydrochloride, a derivative of the amino acid alanine, finds diverse applications in scientific endeavors. Here are the key applications of L-Alanine amide hydrochloride, each presented with a high degree of perplexity and burstiness:

Biochemical Research: Widely employed in biochemical research, L-Alanine amide hydrochloride plays a pivotal role in elucidating enzyme kinetics and substrate specificity. By introducing this compound into enzyme assays, researchers delve into the intricate catalytic mechanisms of enzymes targeting amino acid derivatives. This in-depth exploration contributes to a nuanced comprehension of enzyme functions and unveils potential biotechnological applications with staggering implications.

Pharmaceutical Development: In the pharmaceutical landscape, L-Alanine amide hydrochloride emerges as a crucial intermediary in synthesizing a spectrum of drugs. Its significance lies in fostering the creation of novel therapeutic compounds, particularly those engineered to combat metabolic disorders. As a fundamental building block in drug synthesis, this compound spearheads innovations in medicinal chemistry and propels breakthroughs in drug design, heralding a new era of pharmaceutical advancements.

Peptide Synthesis: At the heart of peptide synthesis, L-Alanine amide hydrochloride assumes a pivotal role in weaving peptide chains together. Its functions are instrumental in establishing stable amide bonds, ensuring the correct folding and optimal functionality of synthesized peptides. This application stands as a cornerstone in diverse realms, from pioneering research in protein engineering and vaccine development to shaping the landscape of peptide-based drug discovery, each endeavor opening new avenues for transformative scientific exploration.

Nutritional Studies: Delving into the realm of nutritional research, L-Alanine amide hydrochloride serves as a linchpin in unraveling the intricacies of amino acid metabolism and bioavailability. By administering labeled L-Alanine amide hydrochloride, scientists trace its metabolic pathways in vivo, navigating the intricate web of protein synthesis and energy production. These enlightening investigations are critical for decoding the nuances of amino acid nutrition and metabolism in varied physiological contexts, illuminating new pathways for understanding the fundamental processes that sustain life.

1.Structure and behaviour of the free radicals generated in gamma irradiated amino acid and iminodiacetic acid derivatives.
Osmanoğlu S1, Aydın M, Osmanoğlu YE, Dicle IY, Başkan MH. Spectrochim Acta A Mol Biomol Spectrosc. 2011 May;78(5):1611-4. doi: 10.1016/j.saa.2011.02.016. Epub 2011 Feb 18.
An EPR study has been carried out to investigate the structure and behaviour of the free radical formed γ-irradiated l-alaninamide hydrochloride, dl-glutamic acid monohydrate and N-(2-carboxyethyl) iminodiacetic acid powders at room temperature. The observed paramagnetic species have been attributed to the CH(3)ĊHCONH(2), HOOCCH(2)CH(2)ĊHCOOH and HOOCCH(2)CH(2)NĊHCH(2)(COOH)(2) radicals, respectively. Some spectroscopic properties and suggestions concerning possible structure of the radicals were also discussed in this study.
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