L-Alanine benzyl ester p-toluenesulfonate salt
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L-Alanine benzyl ester p-toluenesulfonate salt

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A benzoxazine derivatives as modulators of chemokine receptors for treatment of inflammatory and immunoregulatory diseases.

Category
L-Amino Acids
Catalog number
BAT-008034
CAS number
42854-62-6
Molecular Formula
C10H13NO2.C7H8O3S
Molecular Weight
351.41
L-Alanine benzyl ester p-toluenesulfonate salt
IUPAC Name
benzyl (2S)-2-aminopropanoate;4-methylbenzenesulfonic acid
Synonyms
beta-Alanine benzyl ester p-toluenesulfonate
Appearance
White crystal powder
Purity
≥ 99% (HPLC)
Melting Point
114-116 °C
Boiling Point
256.5°C at 760mmHg
Storage
Store at 2-8 °C
Solubility
Soluble in DMSO, Methanol
InChI
InChI=1S/C10H13NO2.C7H8O3S/c1-8(11)10(12)13-7-9-5-3-2-4-6-9;1-6-2-4-7(5-3-6)11(8,9)10/h2-6,8H,7,11H2,1H3;2-5H,1H3,(H,8,9,10)/t8-;/m0./s1
InChI Key
NWOPHJSSBMABBD-QRPNPIFTSA-N
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)O.CC(C(=O)OCC1=CC=CC=C1)N

L-Alanine benzyl ester p-toluenesulfonate salt is a versatile chemical compound with various applications in bioscience and chemistry. Here are some key applications of L-Alanine benzyl ester p-toluenesulfonate salt:

1. Peptide Synthesis: L-Alanine benzyl ester p-toluenesulfonate salt is commonly used as a protected amino acid derivative in peptide synthesis. By providing a stable protecting group, it helps in the stepwise construction of peptides without unwanted side reactions. This is essential for the synthesis of complex peptides and proteins used in research and therapeutic applications.

2. Drug Development: In the pharmaceutical industry, L-Alanine benzyl ester p-toluenesulfonate salt serves as an intermediate in the synthesis of bioactive molecules. Its role as a protected amino acid derivative allows for the precise incorporation of alanine moieties into drug candidates. This is crucial for optimizing pharmacokinetic and pharmacodynamic properties.

3. Enzyme Substrate Studies: The compound can be used as a substrate in enzyme-catalyzed reactions to study enzyme activity and specificity. Researchers utilize L-Alanine benzyl ester p-toluenesulfonate salt to investigate the kinetic parameters and catalytic mechanisms of alanine-specific enzymes. This provides valuable insights into enzyme function and potential applications in biotechnology.

4. Chemical Research: L-Alanine benzyl ester p-toluenesulfonate salt is employed in various organic synthesis protocols as a building block for complex molecules. Its stability and reactivity make it an ideal candidate for developing new synthetic routes and methodologies. This contributes to advancing chemical research and expanding the repertoire of synthetic chemistry.

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