L-Cystine bis-ethyl ester dihydrochloride(Disulfide Bond)
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L-Cystine bis-ethyl ester dihydrochloride(Disulfide Bond)

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Category
L-Amino Acids
Catalog number
BAT-003975
CAS number
22735-07-5
Molecular Formula
C10H20N2O4S2·2HCl
Molecular Weight
369.33
L-Cystine bis-ethyl ester dihydrochloride(Disulfide Bond)
IUPAC Name
ethyl (2R)-2-amino-3-[[(2R)-2-amino-3-ethoxy-3-oxopropyl]disulfanyl]propanoate;dihydrochloride
Synonyms
(H-L-Cys-OEt)2 2HCl; [3-[(2-azaniumyl-3-ethoxy-3-oxopropyl)disulfanyl]-1-ethoxy-1-oxopropan-2-yl]azanium,dichloride; L-Cystin-diethylester; L-cistine diethyl ester dihydrochloride; diethyl L-cystinate dihydrochloride; (H-Cys-OEt)2 2HCl,(Disulfide bond); L-Cystin-diaethylester,Hydrochloride
Appearance
White powder
Purity
≥ 99% (TLC)
Melting Point
190-194 °C
Boiling Point
401.7 °C at 760 mmHg
Storage
Store at -20 °C
InChI
InChI=1S/C10H20N2O4S2.2ClH/c1-3-15-9(13)7(11)5-17-18-6-8(12)10(14)16-4-2;;/h7-8H,3-6,11-12H2,1-2H3;2*1H/t7-,8-;;/m0../s1
InChI Key
BDJZWSLXDLQPNZ-FOMWZSOGSA-N
Canonical SMILES
CCOC(=O)C(CSSCC(C(=O)OCC)N)N.Cl.Cl

L-Cystine bis-ethyl ester dihydrochloride, a compound with diverse applications in science and industry, plays a crucial role in facilitating disulfide bond formation.

Protein Folding Studies: Delving into the intricacies of protein folding and stability, scientists turn to L-Cystine bis-ethyl ester dihydrochloride to introduce disulfide bonds, aiding in the stabilization of protein structures. This enables a meticulous analysis of folding pathways and misfolding mechanisms, pivotal in unraveling the complexities of diseases linked to protein misfolding, such as Alzheimer’s and Parkinson’s.

Biotechnology: Within the realm of biotechnology, L-Cystine bis-ethyl ester dihydrochloride emerges as a valuable asset in enhancing the stability and solubility of recombinant proteins. Through the facilitation of disulfide bonds, this compound boosts thermal stability and shields proteins from degradation, a critical function in the production of biologics and therapeutic proteins.

Cosmetics Industry: The cosmetics sector harnesses the power of L-Cystine bis-ethyl ester dihydrochloride in crafting hair-care solutions geared towards fortifying hair structure and preventing breakage. By fostering disulfide bond formation within the keratin matrix, this compound elevates hair strength and resilience, serving as a cornerstone ingredient in treatments dedicated to rejuvenating chemically damaged hair.

Cell Culture: In the realm of cell culture, L-Cystine bis-ethyl ester dihydrochloride takes on a pivotal role as a growth supplement, nurturing cellular vitality and proliferation. Serving as a wellspring of cystine, it aids in upholding redox balance and overall cellular well-being, a critical factor in cultivating cells with specific growth requirements, including certain mammalian and insect cell lines that thrive on cystine supplementation.

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