Inquiry Basket
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
L-Glutamic acid α-allyl ester γ-2-chlorotrityl resin plays a pivotal role in peptide synthesis within the bioscience sector.
Peptide Synthesis: Utilized in solid-phase peptide synthesis, this resin serves as a robust scaffold for sequentially linking amino acids, facilitating the controlled growth of peptide chains. By offering a stable foundation, it guarantees high yields and purity in synthesized peptides, enabling the creation of intricate peptide structures with precision.
Combinatorial Chemistry: Embraced in combinatorial chemistry, L-Glutamic acid α-allyl ester γ-2-chlorotrityl resin accelerates the generation of extensive libraries of peptide variants. This accelerated approach is indispensable in the quest for novel drugs and bioactive molecules, enabling the rapid screening of diverse compounds. Its exceptional stability and ease of cleavage render it an ideal choice for streamlined, high-throughput synthesis and analysis processes.
Protein Engineering: Facilitating the synthesis of tailored peptides, this resin supports protein engineering endeavors and modification studies. By permitting the integration of non-natural amino acids or chemical alterations, it aids in crafting peptides with augmented stability or modified functionalities. This capability is pivotal in advancing therapeutic protein development and unraveling the intricate relationships between protein structure and function.
