Leu-AMC HCl
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Leu-AMC HCl

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L-Leucine 7-Amido-4-methylcoumarin Hydrochloride is a fluorogenic substrate for LAP3 (leucine aminopeptidase). Upon enzyme activity, a bright blue fluorescent dye, 7-amino-4-methylcoumarin, is released.

Category
Other Unnatural Amino Acids
Catalog number
BAT-007997
CAS number
62480-44-8
Molecular Formula
C16H21ClN2O3
Molecular Weight
324.80
Leu-AMC HCl
IUPAC Name
(2S)-2-amino-4-methyl-N-(4-methyl-2-oxochromen-7-yl)pentanamide;hydrochloride
Synonyms
L-Leucine-AMC.HCl
Related CAS
98516-72-4 (free base)
Appearance
White to Off-white Powder
Purity
≥ 99% (HPLC)
Melting Point
268-272 °C (dec.)
Boiling Point
503°C at 760 mmHg
Storage
Store at 2-8 °C
Solubility
Soluble in methanol
InChI
InChI=1S/C16H20N2O3.ClH/c1-9(2)6-13(17)16(20)18-11-4-5-12-10(3)7-15(19)21-14(12)8-11;/h4-5,7-9,13H,6,17H2,1-3H3,(H,18,20);1H/t13-;/m0./s1
InChI Key
VCRXITKKWBOQRZ-ZOWNYOTGSA-N
Canonical SMILES
CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC(C)C)N.Cl
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