[Leu27]-Melan-A, MART 1 (26-35)
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[Leu27]-Melan-A, MART 1 (26-35)

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[Leu27]-Melan-A, MART 1 (26-35) is an analog of MART-1 (26-35), which is an immunodominant antigen from melanocyte/melanoma (Melan-A/MART) protein. [Leu27]-Melan-A MART 1 (26-35) shows better HLA-A*0201 binding properties as well as better immunogenicity and antigenicity than the natural MART 1 (26-35).

Category
Functional Peptides
Catalog number
BAT-016950
CAS number
204060-45-7
Molecular Formula
C45H80N10O14
Molecular Weight
985.18
[Leu27]-Melan-A, MART 1 (26-35)
IUPAC Name
(4S)-4-amino-5-[[(2S)-1-[[(2S)-1-[[2-[[(2S,3S)-1-[[2-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
Synonyms
H-Glu-Leu-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH; Glu-Leu-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val; Melan-A/MART-1 analog
Appearance
White powder
Sequence
ELAGIGILTV
Storage
Store at -20 °C
InChI
InChI=1S/C45H80N10O14/c1-13-24(9)35(52-31(57)19-47-38(61)26(11)49-40(63)29(17-21(3)4)50-39(62)28(46)15-16-33(59)60)42(65)48-20-32(58)53-36(25(10)14-2)43(66)51-30(18-22(5)6)41(64)55-37(27(12)56)44(67)54-34(23(7)8)45(68)69/h21-30,34-37,56H,13-20,46H2,1-12H3,(H,47,61)(H,48,65)(H,49,63)(H,50,62)(H,51,66)(H,52,57)(H,53,58)(H,54,67)(H,55,64)(H,59,60)(H,68,69)/t24-,25-,26-,27+,28-,29-,30-,34-,35-,36-,37-/m0/s1
InChI Key
QOFFIYNNFILLNX-JPHWTZHESA-N
Canonical SMILES
CC[C@H](C)[C@@H](C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)N
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