Need Assistance?

US & Canada:
+
UK: +

Our Highlights

GMP Grade Efficient workshop for GMP production.
Optimal Prices Buying products on this site guarantees the best price!
Commercial Batches Independent GMP manufacturing suites that handle commercial batches
Prompt Delivery Warehouses in multiple cities to ensure timely delivery
Flexible Quantity Quantities available from milligrams to ton

Leuprolide impurity (1-8)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Leuprolide impurity (1-8) is an impurity of Leuprolide, which is a synthetic nonapeptide analog of gonadotropin-releasing hormone used as an antineoplastic agent, a gonadotropin-releasing hormone agonist, and an anti-estrogen.

Category

Others

Catalog number

BAT-014485

CAS number

112642-14-5

Molecular Formula

C52H72N14O12

Molecular Weight

1085.23

Specification

IUPAC Name

(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-3-hydroxy-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]pentanoic acid

Synonyms

Pyr-His-Trp-Ser-Tyr-D-Leu-Leu-Arg; 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-Seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginine; LHRH (1-8); 1-8-Luteinizing hormone-releasing factor (swine), 6-D-leucine-; Luteinizing hormone-releasing factor (pig), 6-D-leucine-9-de-L-proline-10-deglycinamide-; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginine

Appearance

Off-white Lyophilized Powder

Purity

≥95% by HPLC

Density

1.47±0.1 g/cm3

Boiling Point

1319.5±75.0°C at 760 mmHg

Sequence

Pyr-HWSYlLR

Storage

Store at -20°C, protect from light and moisture

Solubility

Soluble in Water

InChI

InChI=1S/C52H72N14O12/c1-27(2)18-37(45(71)60-36(51(77)78)10-7-17-56-52(53)54)61-46(72)38(19-28(3)4)62-47(73)39(20-29-11-13-32(68)14-12-29)63-50(76)42(25-67)66-48(74)40(21-30-23-57-34-9-6-5-8-33(30)34)64-49(75)41(22-31-24-55-26-58-31)65-44(70)35-15-16-43(69)59-35/h5-6,8-9,11-14,23-24,26-28,35-42,57,67-68H,7,10,15-22,25H2,1-4H3,(H,55,58)(H,59,69)(H,60,71)(H,61,72)(H,62,73)(H,63,76)(H,64,75)(H,65,70)(H,66,74)(H,77,78)(H4,53,54,56)/t35-,36-,37-,38+,39-,40-,41-,42-/m0/s1

InChI Key

ZLQKBMAVTAPWOL-YVQQOERGSA-N

Canonical SMILES

CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CO)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CN=CN4)NC(=O)C5CCC(=O)N5