(Lys22)-Amyloid β-Protein (1-40)

(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-6-amino-1-[[2-[[(2S)-1-[[(2S,3S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[2-[[(2S)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-amino-3-carboxypropanoyl]amino]propanoyl]amino]-5-oxopentanoic acid

Amyloid β-Protein (1-40) Italian Mutation; H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH; L-Valine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-arginyl-L-histidyl-L-α-aspartyl-L-serylglycyl-L-tyrosyl-L-α-glutamyl-L-valyl-L-histidyl-L-histidyl-L-glutaminyl-L-lysyl-L-leucyl-L-valyl-L-phenylalanyl-L-phenylalanyl-L-alanyl-L-lysyl-L-α-aspartyl-L-valylglycyl-L-seryl-L-asparaginyl-L-lysylglycyl-L-alanyl-L-isoleucyl-L-isoleucylglycyl-L-leucyl-L-methionyl-L-valylglycylglycyl-L-valyl-

White Lyophilized Powder

≥95%

DAEFRHDSGYEVHHQKLVFFAKDVGSNKGAIIGLMVGGVV

Store at -20°C

Soluble in Acetic Acid

InChI=1S/C195H300N54O56S/c1-25-104(19)159(189(299)213-89-145(258)220-126(69-96(3)4)175(285)230-125(63-68-306-24)173(283)243-153(98(7)8)187(297)211-85-142(255)208-86-147(260)242-155(100(11)12)192(302)247-158(103(17)18)194(304)305)249-193(303)160(105(20)26-2)248-163(273)106(21)217-143(256)87-209-165(275)118(49-36-39-64-196)225-182(292)135(79-141(201)254)236-186(296)139(92-251)222-146(259)90-212-188(298)154(99(9)10)244-185(295)137(81-152(269)270)237-167(277)119(50-37-40-65-197)223-162(272)108(23)219-174(284)129(71-109-43-30-27-31-44-109)233-178(288)131(73-111-47-34-29-35-48-111)239-190(300)157(102(15)16)246-184(294)127(70-97(5)6)231-168(278)120(51-38-41-66-198)226-170(280)122(57-60-140(200)253)228-179(289)132(75-113-82-204-93-214-113)235-181(291)134(77-115-84-206-95-216-115)240-191(301)156(101(13)14)245-172(282)124(59-62-149(263)264)229-176(286)128(74-112-53-55-116(252)56-54-112)221-144(257)88-210-166(276)138(91-250)241-183(293)136(80-151(267)268)238-180(290)133(76-114-83-205-94-215-114)234-169(279)121(52-42-67-207-195(202)203)227-177(287)130(72-110-45-32-28-33-46-110)232-171(281)123(58-61-148(261)262)224-161(271)107(22)218-164(274)117(199)78-150(265)266/h27-35,43-48,53-56,82-84,93-108,117-139,153-160,250-252H,25-26,36-42,49-52,57-81,85-92,196-199H2,1-24H3,(H2,200,253)(H2,201,254)(H,204,214)(H,205,215)(H,206,216)(H,208,255)(H,209,275)(H,210,276)(H,211,297)(H,212,298)(H,213,299)(H,217,256)(H,218,274)(H,219,284)(H,220,258)(H,221,257)(H,222,259)(H,223,272)(H,224,271)(H,225,292)(H,226,280)(H,227,287)(H,228,289)(H,229,286)(H,230,285)(H,231,278)(H,232,281)(H,233,288)(H,234,279)(H,235,291)(H,236,296)(H,237,277)(H,238,290)(H,239,300)(H,240,301)(H,241,293)(H,242,260)(H,243,283)(H,244,295)(H,245,282)(H,246,294)(H,247,302)(H,248,273)(H,249,303)(H,261,262)(H,263,264)(H,265,266)(H,267,268)(H,269,270)(H,304,305)(H4,202,203,207)/t104-,105-,106-,107-,108-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,153-,154-,155-,156-,157-,158-,159-,160-/m0/s1

RVGDRHRMLHDURP-WNKKHKIDSA-N

CCC(C)C(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)NC(C(C)C)C(=O)NCC(=O)NCC(=O)NC(C(C)C)C(=O)NC(C(C)C)C(=O)O)NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)CNC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)N)NC(=O)C(CC3=CN=CN3)NC(=O)C(CC4=CN=CN4)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CC(=O)O)NC(=O)C(CC6=CN=CN6)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CC(=O)O)N