L-Lysyl-L-glutamine
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L-Lysyl-L-glutamine

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L-Lysyl-L-glutamine is a dipeptide made up of L-lysine and L-glutamine. L-lysine is an essential amino acid important for protein synthesis, tissue repair, and the production of enzymes and hormones, while L-glutamine supports immune function, nitrogen transport, and intestinal health. This dipeptide could be of interest in studies exploring amino acid supplementation, protein metabolism, or immune system support, as well as in potential therapeutic applications targeting muscle recovery or gut health.

Category
Peptide Synthesis Reagents
Catalog number
BAT-016603
CAS number
92352-82-4
Molecular Formula
C11H22N4O4
Molecular Weight
274.32
L-Lysyl-L-glutamine
IUPAC Name
(2S)-5-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-oxopentanoic acid
Synonyms
KQ; Lysyl-glutamine; H-Lys-Gln-OH; H-KQ-OH; Lys-Gln; L-Glutamine, N2-L-lysyl-; Lysylglutamine; KQ dipeptide; K-Q Dipeptide; L-Lys-L-Gln; Lysine Glutamine dipeptide
Related CAS
92352-83-5 (homopolymer)
Appearance
Solid
Purity
≥95%
Density
1.249±0.06 g/cm3
Boiling Point
673.9±55.0 °C at 760 mmHg
Sequence
Lys-Gln
Solubility
Soluble in Water
InChI
InChI=1S/C11H22N4O4/c12-6-2-1-3-7(13)10(17)15-8(11(18)19)4-5-9(14)16/h7-8H,1-6,12-13H2,(H2,14,16)(H,15,17)(H,18,19)/t7-,8-/m0/s1
InChI Key
OAPNERBWQWUPTI-YUMQZZPRSA-N
Canonical SMILES
C(CCN)CC(C(=O)NC(CCC(=O)N)C(=O)O)N
1. Purification of a synthetic myristylated peptide by counter-current chromatography
M Knight, S Gluch, K Takahashi, T T Dang, R A Kahn J Chromatogr. 1991 Jan 18;538(1):141-7. doi: 10.1016/s0021-9673(01)91631-0.
A preparative purification of myristyl-Gly-Asn-Ile-Phe-Ala-Asn-Leu-Phe-Lys-Gly-Leu-Phe-Gly-Lys-Lys-Glu -NH2 was accomplished using the multi-coil counter-current chromatograph. A partition coefficient was determined in the n-butanol-acetic acid-water (4:1:5) system. Chromatographic runs were made in this system and one modified with ethyl acetate. The peptide material showed anomalous elution behavior due to its surfactant properties. It was found that by loading the sample exclusively in the stationary phase, satisfactory retention of the compound occurred. Finally, conditions utilizing the upper phase as the mobile phase successfully separated the impurities.
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