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Mastoparan-A

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Mastoparan-A exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes. It has a role as an antibacterial agent.

Category
Functional Peptides
Catalog number
BAT-011991
Molecular Formula
C79H138N20O16
Molecular Weight
1624.1
IUPAC Name
(3S)-4-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S,3S)-1-amino-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]hexanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoic acid
Synonyms
MP-A
Sequence
IKWKAILDAVKKVL
InChI
InChI=1S/C79H138N20O16/c1-15-45(10)61(84)76(112)91-54(31-21-25-35-81)71(107)93-58(39-50-41-86-52-29-19-18-28-51(50)52)75(111)90-53(30-20-24-34-80)69(105)87-49(14)68(104)99-65(47(12)17-3)79(115)95-57(38-42(4)5)74(110)94-59(40-60(100)101)73(109)88-48(13)67(103)96-62(43(6)7)77(113)92-55(32-22-26-36-82)70(106)89-56(33-23-27-37-83)72(108)97-63(44(8)9)78(114)98-64(66(85)102)46(11)16-2/h18-19,28-29,41-49,53-59,61-65,86H,15-17,20-27,30-40,80-84H2,1-14H3,(H2,85,102)(H,87,105)(H,88,109)(H,89,106)(H,90,111)(H,91,112)(H,92,113)(H,93,107)(H,94,110)(H,95,115)(H,96,103)(H,97,108)(H,98,114)(H,99,104)(H,100,101)/t45-,46-,47-,48-,49-,53-,54-,55-,56-,57-,58-,59-,61-,62-,63-,64-,65-/m0/s1
InChI Key
CPTNXTSDQJQEFA-ZKOWQLKRSA-N
Canonical SMILES
CCC(C)C(C(=O)NC(CCCCN)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(C(C)CC)C(=O)N)N
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