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MC-Gly-Gly-Phe-Gly

Name: MC-Gly-Gly-Phe-Gly
Brand: BOC Sciences
Rating: 5 (1 reviews)

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

MC-Gly-Gly-Phe-Gly is a cleavable ADC linker used for antibody-drug conjugates (ADCs).

Category

Others

Catalog number

BAT-009091

CAS number

2413428-36-9

Molecular Formula

C25H31N5O8

Molecular Weight

529.54

Specification

IUPAC Name

2-[[(2S)-2-[[2-[[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]acetic acid

Synonyms

(S)-5-Benzyl-18-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaoctadecan-1-oic acid

Appearance

Solid Powder

Purity

>98.0%

Density

1.331±0.06 g/cm3(Predicted)

Boiling Point

1009.8±65.0°C(Predicted)

Sequence

MC-Gly-Gly-Phe-Gly

Storage

Store at -20 °C, keep in dry and avoid sunlight.

Solubility

10 mm in DMSO

InChI

InChI=1S/C25H31N5O8/c31-19(9-5-2-6-12-30-22(34)10-11-23(30)35)26-14-20(32)27-15-21(33)29-18(25(38)28-16-24(36)37)13-17-7-3-1-4-8-17/h1,3-4,7-8,10-11,18H,2,5-6,9,12-16H2,(H,26,31)(H,27,32)(H,28,38)(H,29,33)(H,36,37)/t18-/m0/s1

InChI Key

DWPLKZYCOGLRPC-SFHVURJKSA-N

Canonical SMILES

C1=CC=C(C=C1)CC(C(=O)NCC(=O)O)NC(=O)CNC(=O)CNC(=O)CCCCCN2C(=O)C=CC2=O