MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category
Others
Catalog number
BAT-010701
CAS number
1599440-25-1
Molecular Formula
C28H36N6O10
Molecular Weight
616.62
MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
Size Price Stock Quantity
10 mg $939 In stock
IUPAC Name
2-[[(2-amino-2-oxoethyl)-[(2S)-2-[[2-[[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]methoxy]acetic acid
Synonyms
Glycinamide,N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]glycylglycyl-L-phenylalanyl-N-[(carboxymethoxy) methyl]-
Appearance
Solid
Purity
>98.0%
Density
1.341±0.06 g/cm3(Predicted)
Boiling Point
1137.9±65.0°C(Predicted)
Storage
Store at -20 °C, keep in dry and avoid sunlight.
Solubility
10 mm in DMSO
InChI
InChI=1S/C28H36N6O10/c29-21(35)16-33(18-44-17-27(41)42)28(43)20(13-19-7-3-1-4-8-19)32-24(38)15-31-23(37)14-30-22(36)9-5-2-6-12-34-25(39)10-11-26(34)40/h1,3-4,7-8,10-11,20H,2,5-6,9,12-18H2,(H2,29,35)(H,30,36)(H,31,37)(H,32,38)(H,41,42)/t20-/m0/s1
InChI Key
KESCPWCFEIIACU-FQEVSTJZSA-N
Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)N(CC(=O)N)COCC(=O)O)NC(=O)CNC(=O)CNC(=O)CCCCCN2C(=O)C=CC2=O
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