Murepavadin TFA
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Murepavadin TFA

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Murepavadin (TFA), a 14-amino acid cyclic peptide, is a highly effective, specific antibiotic for the treatment of bacterial infections caused by Pseudomonas aeruginosa. Murepavadin (TFA) targets the lipopolysaccharide transport protein D.

Category
Functional Peptides
Catalog number
BAT-009288
Molecular Formula
C73H112N22O16.C2HF3O2
Molecular Weight
1667.83
IUPAC Name
(3R,9S,12S,15S,18S,21S,24S,27R,30S,33S,36S,39S,42S,45S)-15,18,24,27,33-pentakis(2-aminoethyl)-30-(3-aminopropyl)-36-[(2S)-butan-2-yl]-42-[(1R)-1-hydroxyethyl]-9-(hydroxymethyl)-21,39-bis(1H-indol-3-ylmethyl)-12-methyl-1,7,10,13,16,19,22,25,28,31,34,37,40,43-tetradecazatricyclo[43.3.0.03,7]octatetracontane-2,8,11,14,17,20,23,26,29,32,35,38,41,44-tetradecone; 2,2,2-trifluoroacetic acid
Synonyms
POL7080 (TFA); Cyclo(Ala-Ser-d-Pro-Pro-Thr-Trp-Ile-Dab-Orn-d-Dab-Dab-Trp-Dab-Dab).TFA; Murepavadin trifluoroacetic acid
Related CAS
944252-63-5 (free base)
Appearance
Powder
Purity
>98%
Sequence
Cyclo(AS-d-Pro-PTWI-Dab-Orn-d-Dab-Dab-W-Dab-Dab).TFA
Storage
Store at -20°C
Solubility
Soluble in Water
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