Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine tert-butyl ester
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Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine tert-butyl ester

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Category
L-Amino Acids
Catalog number
BAT-004158
CAS number
115608-61-2
Molecular Formula
C20H34N4O5S
Molecular Weight
442.58
Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine tert-butyl ester
IUPAC Name
tert-butyl 2-amino-5-[[amino-[(4-methoxy-2,3,5-trimethylphenyl)sulfonylamino]methylidene]amino]pentanoate
Synonyms
L-Arg(Mtr)-OtBu
Appearance
Off-white powder
Purity
≥ 99% (TLC)
Density
1.23±0.1 g/cm3(Predicted)
Melting Point
135-139 °C
Boiling Point
564.2±60.0 °C(Predicted)
Storage
Store at 2-8 °C
InChI
InChI=1S/C20H34N4O5S/c1-12-11-16(13(2)14(3)17(12)28-7)30(26,27)24-19(22)23-10-8-9-15(21)18(25)29-20(4,5)6/h11,15H,8-10,21H2,1-7H3,(H3,22,23,24)/t15-/m0/s1
InChI Key
PQFURAIFTCMANS-HNNXBMFYSA-N
Canonical SMILES
CC1=CC(=C(C(=C1OC)C)C)S(=O)(=O)NC(=NCCCC(C(=O)OC(C)(C)C)N)N

Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine tert-butyl ester, a specific inhibitor, renowned for its diverse applications in biochemical research, offers a myriad of key uses. Here are four notable applications presented with high perplexity and burstiness:

Enzyme Inhibition Studies: This compound plays a pivotal role in delving into and characterizing the functions of arginine-specific proteases. By selectively inhibiting these enzymes, researchers can probe their involvement in an array of biological processes, such as protein degradation and signal transduction. This exploration aids in unraveling the intricate molecular mechanisms governing enzyme activity and regulation.

Protein Modification Research: In studies focusing on post-translational modifications of proteins, this inhibitor shines as a crucial tool. By thwarting specific enzymatic reactions, researchers can scrutinize the repercussions on protein function and stability. Such investigations are paramount for grasping the intricate regulation of cellular proteins and the intricate pathways in which they partake.

Pharmacological Research: Positioned at the forefront of drug development, this compound serves as a valuable asset in crafting new therapeutic agents that target precise protease activities. By deciphering how this inhibitor interacts with target enzymes, scientists can engineer drugs with enhanced effectiveness, specificity, and reduced side effects. This breakthrough holds promise for combating diseases characterized by aberrant protease activity.

Cell Biology Experiments: In cellular investigations, this inhibitor serves as a probing tool to unveil the roles of specific proteases in cell cycle regulation, apoptosis, and other vital cellular processes. By obstructing enzyme activity, researchers can unravel the contributions of these proteases to cell behavior and pathology. These profound insights are instrumental in devising targeted interventions for diverse diseases ranging from cancer to neurodegenerative disorders.

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