Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
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Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine

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Category
L-Amino Acids
Catalog number
BAT-004157
CAS number
80745-10-4
Molecular Formula
C16H26N4O5S
Molecular Weight
386.50
Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine
IUPAC Name
(2S)-2-amino-5-[[amino-[(4-methoxy-2,3,6-trimethylphenyl)sulfonylamino]methylidene]amino]pentanoic acid
Synonyms
L-Arg(Mtr)-OH; Nomega-(4-Methoxy-2,3,6-Trimethylbenzenesulfonyl)-D-Arginine; N Pound Inverted Question Mark(4-Methoxy-2,3,6-Trimethylbenzenesulfonyl)-L-Arginine
Appearance
White powder
Purity
≥ 98% (HPLC)
Density
1.36 g/cm3
Boiling Point
615.4°C
Storage
Store at 2-8 °C
InChI
InChI=1S/C16H26N4O5S/c1-9-8-13(25-4)10(2)11(3)14(9)26(23,24)20-16(18)19-7-5-6-12(17)15(21)22/h8,12H,5-7,17H2,1-4H3,(H,21,22)(H3,18,19,20)/t12-/m0/s1
InChI Key
FUSAEZSSVDNYPO-LBPRGKRZSA-N
Canonical SMILES
CC1=CC(=C(C(=C1S(=O)(=O)NC(=NCCCC(C(=O)O)N)N)C)C)OC

Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine, a synthetic compound used in various biochemical and pharmaceutical research endeavors, exhibits diverse applications in the following areas:

Enzyme Inhibition Studies: A key application involves employing Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine as an inhibitor in investigations related to nitric oxide synthase (NOS) enzymes. By selectively targeting NOS, researchers delve into the intricate roles of nitric oxide in physiological and pathological processes. This exploration aids in crafting therapeutic interventions for disorders stemming from nitric oxide dysregulation, such as inflammatory conditions and cardiovascular ailments.

Exploration of Arginine Metabolism: This compound serves as a powerful tool for delving into the convoluted pathways associated with arginine metabolism. Through the inhibition of specific enzymes, it sheds light on the intricate regulation and functionalities of arginine and its metabolic byproducts. Such investigations play a pivotal role in deciphering diseases linked to amino acid metabolism and in developing precisely targeted therapeutic modalities.

Pharmacological Endeavors: In the realm of pharmacology, Nω-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine finds utility in crafting novel drugs that target enzymes utilizing arginine. Scientists leverage the effects of this compound on diverse biological pathways to pave the way for the discovery and design of innovative therapeutic agents. Acting as a lead compound, it aids in the development of more potent and selective enzyme inhibitors.

Cell Signaling Pathways: This compound’s significance extends to the realm of cell signaling pathways, particularly those involving the pivotal role of nitric oxide. By hindering nitric oxide production, researchers dissect the intricate networks and mechanisms governed by nitric oxide and its cascading effects. This profound exploration enhances our comprehension of cellular communication and signal transduction processes, offering a potential avenue for therapeutic breakthroughs in fields like oncology and neurology.

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