N-α-(4-Methoxybenzenesulfonyl)-D-arginine
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N-α-(4-Methoxybenzenesulfonyl)-D-arginine

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Category
D-Amino Acids
Catalog number
BAT-005907
CAS number
200188-25-6
Molecular Formula
C13H20N4O5S
Molecular Weight
344.39
N-α-(4-Methoxybenzenesulfonyl)-D-arginine
IUPAC Name
(2R)-5-(diaminomethylideneamino)-2-[(4-methoxyphenyl)sulfonylamino]pentanoic acid
Synonyms
Mbs-D-Arg-OH
Purity
95%
Density
1.45±0.1 g/cm3
Boiling Point
582.2±60.0 °C
Storage
Store at -20°C
InChI
InChI=1S/C13H20N4O5S/c1-22-9-4-6-10(7-5-9)23(20,21)17-11(12(18)19)3-2-8-16-13(14)15/h4-7,11,17H,2-3,8H2,1H3,(H,18,19)(H4,14,15,16)/t11-/m1/s1
InChI Key
RPFYHHDKHXNWQH-LLVKDONJSA-N
Canonical SMILES
COC1=CC=C(C=C1)S(=O)(=O)NC(CCCN=C(N)N)C(=O)O

N-α-(4-Methoxybenzenesulfonyl)-D-arginine, a synthetic compound with diverse applications in biochemical and medical research, finds itself at the heart of cutting-edge scientific endeavors. Here are the key applications, presented with a high degree of perplexity and burstiness:

Protease Inhibition Studies: Central to biochemical investigations, N-α-(4-Methoxybenzenesulfonyl)-D-arginine serves as a potent tool for selectively inhibiting specific proteases in experimental settings. By arresting protease activity, researchers can delve into the intricate roles these enzymes play in diverse biological processes, ranging from protein degradation to signal transduction. This compound plays a pivotal role in unraveling enzyme mechanisms and pinpointing potential targets for therapeutic intervention.

Pharmaceutical Research: In the quest for groundbreaking drugs, N-α-(4-Methoxybenzenesulfonyl)-D-arginine emerges as a critical asset for screening protease inhibitors. By evaluating its impact on target proteases, scientists can fine-tune inhibitors for heightened efficacy and specificity. This meticulous optimization process is a cornerstone in the discovery of novel therapeutic agents targeting protease-related disorders, pushing the boundaries of pharmaceutical innovation.

Structural Biology: Offering a window into the molecular realm, N-α-(4-Methoxybenzenesulfonyl)-D-arginine plays a pivotal role in crystallography studies aimed at unraveling the structures of protease-inhibitor complexes. By binding to proteases' active sites, this compound allows researchers to visualize the intricate molecular interactions within the enzyme's catalytic domain. Such structural insights are indispensable for rational drug design and decoding enzyme specificity, driving advances in structural biology and drug development.

Biomedical Research: At the forefront of biomedical exploration, this compound is a linchpin in studying the physiological and pathological impacts of proteases. By selectively inhibiting specific proteases, researchers can dissect how these enzymes influence crucial processes like inflammation, coagulation, and cancer progression. These invaluable insights form the foundation for developing novel diagnostic tools and innovative therapeutic approaches, shaping the landscape of biomedical research and clinical practice.

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