N-β-(9-Fluorenylmethoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine
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N-β-(9-Fluorenylmethoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine

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Category
Fmoc-Amino Acids
Catalog number
BAT-004701
CAS number
269396-69-2
Molecular Formula
C24H22N2O4
Molecular Weight
402.45
N-β-(9-Fluorenylmethoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine
IUPAC Name
(3R)-3-(9H-fluoren-9-ylmethoxycarbonylamino)-4-pyridin-4-ylbutanoic acid
Synonyms
Fmoc-D-Ala(4-Pyri)-(C#CH2)OH; (R)-3-[(9-Fluorenylmethoxycarbonyl)amino]-4-(4-pyridyl)butanoic acid
Purity
95%
Density
1.285g/cm3
Boiling Point
658.9°C at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C24H22N2O4/c27-23(28)14-17(13-16-9-11-25-12-10-16)26-24(29)30-15-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-12,17,22H,13-15H2,(H,26,29)(H,27,28)/t17-/m1/s1
InChI Key
ZHEGVQVHZCLRTM-QGZVFWFLSA-N
Canonical SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CC=NC=C4)CC(=O)O

N-β-(9-Fluorenylmethoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine emerges as a chemically distinct amino acid derivative widely utilized in peptide synthesis. Here are the key applications of this compound presented with high perplexity and burstiness:

Peptide Synthesis: Serving as a fundamental element in peptide construction, N-β-(9-Fluorenylmethoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine functions as a versatile building block that allows for the precise incorporation of specific functional groups into peptide sequences. This unique feature enables the synthesis of peptides with heightened stability, enhanced binding affinity, and increased biological activity, offering a myriad of possibilities for peptide design and application.

Drug Development: Exercise caution when exploring the crucial role of this compound in the development of peptide-based pharmaceuticals. By integrating N-β-(9-Fluorenylmethoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine into therapeutic peptides, researchers gain the ability to optimize the pharmacokinetic properties of these medications. This strategic incorporation helps improve bioavailability, prevent degradation, and enhance overall therapeutic efficacy, opening new avenues for drug design and precision medicine.

Bioconjugation: Playing a pivotal role in bioconjugation efforts, N-β-(9-Fluorenylmethoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine emerges as a valuable tool for linking peptides to a diverse range of biomolecules, including proteins, antibodies, and nanoparticles. This conjugation is essential for targeted drug delivery, advanced imaging techniques, and diagnostic applications, showcasing the versatility and utility of this compound in the field of biomedicine. Notably, the presence of the fluorenylmethoxycarbonyl (Fmoc) moiety simplifies the synthesis process and enhances handling efficiency.

Protein Engineering: Embark on a journey into the world of protein engineering with confidence, as this compound seamlessly integrates into proteins to illuminate intricate structure-function relationships. Leveraging N-β-(9-Fluorenylmethoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine enables researchers to introduce precise site-specific modifications and analyze their effects on protein folding kinetics, stability, and functional properties. This innovative approach drives the creation of cutting-edge proteins tailored for diverse industrial and therapeutic applications, heralding a new era of customized protein design and engineering.

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