N-α-Acetyl-L-alanine 1-naphthyl ester
Need Assistance?
  • US & Canada:
    +
  • UK: +

N-α-Acetyl-L-alanine 1-naphthyl ester

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Category
L-Amino Acids
Catalog number
BAT-006902
CAS number
69975-68-4
Molecular Formula
C15H15NO3
Molecular Weight
257.29
N-α-Acetyl-L-alanine 1-naphthyl ester
IUPAC Name
naphthalen-1-yl (2S)-2-acetamidopropanoate
Synonyms
Ac-Ala-ONaph(1); Ac-Ala-α-naphthyl ester
Purity
99%
Density
1.185 g/cm3
Boiling Point
490.1°C at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C15H15NO3/c1-10(16-11(2)17)15(18)19-14-9-5-7-12-6-3-4-8-13(12)14/h3-10H,1-2H3,(H,16,17)/t10-/m0/s1
InChI Key
QLHFGNPCPMZWQU-JTQLQIEISA-N
Canonical SMILES
CC(C(=O)OC1=CC=CC2=CC=CC=C21)NC(=O)C

N-α-Acetyl-L-alanine 1-naphthyl ester, a versatile chemical compound, finds applications in biochemical research and industrial processes. Here are the key applications expressed with high perplexity and burstiness:

Biochemical Assays: Widely employed as a substrate in enzymatic assays, N-α-Acetyl-L-alanine 1-naphthyl ester serves as a pivotal tool for evaluating the activity of proteases and peptidases. By monitoring the hydrolysis of this ester, researchers can precisely quantify enzyme activity across diverse biological samples. This application is indispensable for conducting in-depth studies on enzyme kinetics and facilitating breakthroughs in drug discovery research.

Pharmaceutical Synthesis: Positioned as a key intermediate in synthesizing various pharmaceutical agents, this compound exhibits remarkable reactivity and structural characteristics that render it invaluable for constructing bespoke peptide sequences and drug molecules. Leveraging N-α-Acetyl-L-alanine 1-naphthyl ester can significantly enhance the efficiency and specificity of synthetic pathways within the realm of medicinal chemistry.

Protein Structure Studies: Offering a window into protein dynamics, N-α-Acetyl-L-alanine 1-naphthyl ester serves as a potent tool in dissecting substrate binding and enzymatic mechanisms. By integrating this ester into protein crystals, researchers can delve into the intricate interactions between enzymes and substrates at a molecular scale. This profound insight is pivotal for designing potent enzyme inhibitors and fine-tuning biocatalysts for enhanced performance.

Education and Training: Within academic settings, N-α-Acetyl-L-alanine 1-naphthyl ester assumes the role of a foundational teaching aid in biochemistry courses. It empowers students to grasp the nuances of enzyme kinetics, substrate specificity, and the underlying principles of biochemical assays. This hands-on approach not only enriches theoretical knowledge but also fosters a practical comprehension of enzyme activity and protein chemistry, nurturing the next generation of biochemists and researchers.

1. Di(1-naphthyl) methanol ester of carboxylic acids for absolute stereochemical determination
Jun Zhang, Wei Sheng, Hadi Gholami, Tatsuo Nehira, Babak Borhan Chirality. 2018 Feb;30(2):141-146. doi: 10.1002/chir.22775. Epub 2017 Nov 8.
The absolute stereochemistry of chiral carboxylic acids is determined as a di(1-naphthyl)methanol ester derivative. Computational scoring of conformations favoring either P or M helicity of the naphthyl groups, capable of exciton-coupled circular dichroic coupling, leads to a predicted stereochemistry for the derivatized carboxylic acids.
Online Inquiry
Inquiry Basket