N-Boc-4-oxo-L-proline (BAT-000782)
* For research use only

A reagent used in the syntheisis of benzidine and diaminofluorene prolinamide derivatives which are highly potent HCV inhibitors.

Category
BOC-Amino Acids
Catalog number
BAT-000782
CAS number
84348-37-8
Molecular Formula
C10H15NO5
Molecular Weight
229.23
N-Boc-4-oxo-L-proline
Synonyms
Boc-4-oxo-Pro-OH; (S)-1-(Tert-Butoxycarbonyl)-4-oxopyrrolidine-2-carboxylic acid; N-t-boc-4-oxo-L-proline; N-tert-Boc-4-oxo-L-proline
Purity
98%
Melting Point
160 °C (dec.)
Storage
Store at 2-8 °C
1.Practical synthesis of Boc-protected cis-4-trifluoromethyl and cis-4-difluoromethyl-L- prolines.
Qiu XL1, Qing FL. J Org Chem. 2002 Oct 4;67(20):7162-4.
A short, efficient, and diastereomerically pure synthesis of N-Boc-cis-4-trifluoromethyl-L-proline (7) and N-Boc-cis-4-difluoromethyl-L-proline (9) from N-Boc-4-oxo-L-proline (4) is described. The reaction of 4 with Me(3)SiCF(3) and the conversion of the carbonyl group of 4 into the difluoromethylene group are the key steps for the synthesis of 7 and 9, respectively.
Bio Calculators
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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g
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