Nβ-Boc-L-β-homoglutamine
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Nβ-Boc-L-β-homoglutamine

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Category
BOC-Amino Acids
Catalog number
BAT-007598
CAS number
336182-06-0
Molecular Formula
C11H20N2O5
Molecular Weight
260.29
Nβ-Boc-L-β-homoglutamine
IUPAC Name
(3S)-6-amino-3-[(2-methylpropan-2-yl)oxycarbonylamino]-6-oxohexanoic acid
Synonyms
(S)-3-(Boc-amino)adipic acid 6-amide; Nβ-Boc-L-β-homoglutamine; Boc-L-beta-Homoglutamine; (S)-6-Amino-3-((tert-butoxycarbonyl)amino)-6-oxohexanoic acid; Boc-L-beta-HomoGln-OH; Boc-(S)-3,6-Diamino-6-oxohexanoic acid; Boc-HoGln-OH; Boc-I(2)-HoGln-OH; Boc L beta HomoGln OH
Appearance
White to off-white powder
Purity
≥ 98% (NMR)
Density
1.192±0.06 g/cm3 (Predicted)
Boiling Point
518.9±45.0 °C (Predicted)
Storage
Store at 2-8 °C
InChI
InChI=1S/C11H20N2O5/c1-11(2,3)18-10(17)13-7(6-9(15)16)4-5-8(12)14/h7H,4-6H2,1-3H3,(H2,12,14)(H,13,17)(H,15,16)/t7-/m0/s1
InChI Key
DAUHTFNYHSOVRQ-ZETCQYMHSA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(CCC(=O)N)CC(=O)O

Nβ-Boc-L-β-homoglutamine is a chemical compound used in various scientific research and industrial applications. Here are some key applications of Nβ-Boc-L-β-homoglutamine:

Peptide Synthesis: Nβ-Boc-L-β-homoglutamine is commonly used as a building block in peptide synthesis. Its protection group Boc (tert-butoxycarbonyl) is particularly useful in preventing unwanted reactions during the synthetic process. This enables researchers to develop complex peptides with specific functions for pharmaceutical and biochemical applications.

Drug Development: The Nβ-Boc-L-β-homoglutamine structure aids in the development of new pharmaceuticals, particularly in designing prodrugs. By utilizing this compound in drug synthesis, researchers can enhance the stability and bioavailability of therapeutic agents. This plays a crucial role in the creation of targeted medications with improved efficacy.

Protein Engineering: In the field of protein engineering, Nβ-Boc-L-β-homoglutamine can be used to incorporate modified amino acid residues into proteins. This modification allows for the exploration of protein structure-function relationships and the development of proteins with novel properties. Such engineered proteins can have applications in areas like biotechnology and therapeutics.

Biochemical Studies: Nβ-Boc-L-β-homoglutamine can be employed in biochemical research to investigate enzyme activity and substrate specificity. By integrating this compound into assays, scientists can study its interactions with enzymes and other proteins. This research aids in discovering potential enzyme inhibitors or activators, providing insights for designing new biochemical tools and treatments.

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