Nα-Boc-Nδ-xanthyl-L-glutamine
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Nα-Boc-Nδ-xanthyl-L-glutamine

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Category
BOC-Amino Acids
Catalog number
BAT-002969
CAS number
55260-24-7
Molecular Formula
C23H26N2O6
Molecular Weight
426.50
Nα-Boc-Nδ-xanthyl-L-glutamine
IUPAC Name
(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxo-5-(9H-xanthen-9-ylamino)pentanoic acid
Synonyms
Boc-L-Gln(Xan)-OH
Appearance
White powder
Purity
≥ 99% (HPLC)
Density
1.30±0.1 g/cm3(Predicted)
Melting Point
145-175 °C
Boiling Point
669.8±55.0 °C(Predicted)
Storage
Store at 2-8°C
InChI
InChI=1S/C23H26N2O6/c1-23(2,3)31-22(29)24-16(21(27)28)12-13-19(26)25-20-14-8-4-6-10-17(14)30-18-11-7-5-9-15(18)20/h4-11,16,20H,12-13H2,1-3H3,(H,24,29)(H,25,26)(H,27,28)/t16-/m0/s1
InChI Key
HOIIDGIJEPOSLL-INIZCTEOSA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(CCC(=O)NC1C2=CC=CC=C2OC3=CC=CC=C13)C(=O)O

Nα-Boc-Nδ-xanthyl-L-glutamine is a derivative of the amino acid glutamine and is primarily used in peptide synthesis and biochemical research. Here are some key applications of Nα-Boc-Nδ-xanthyl-L-glutamine:

Peptide Synthesis: In the field of peptide synthesis, Nα-Boc-Nδ-xanthyl-L-glutamine serves as a protected amino acid building block. Its Boc (tert-butyloxycarbonyl) group protects the amino group during peptide chain assembly, preventing unwanted side reactions. This derivative facilitates the synthesis of complex peptides by ensuring selective reactions and improving overall yield.

Biochemical Research: Researchers employ Nα-Boc-Nδ-xanthyl-L-glutamine in studying protein structures and functions. By incorporating this derivative into peptides or proteins, scientists can investigate the role of glutamine residues in enzymatic activity and protein-protein interactions. It serves as a valuable tool for probing the structural and functional aspects of biomolecules in various biological systems.

Drug Development: In drug discovery, Nα-Boc-Nδ-xanthyl-L-glutamine can aid in the development of therapeutic agents. Its incorporation into peptide-based drug candidates allows for the exploration of structure-activity relationships. This can lead to the identification of potent and selective compounds for targeting specific diseases or biological pathways.

Chemical Biology: Nα-Boc-Nδ-xanthyl-L-glutamine is utilized in chemical biology to study cellular mechanisms and pathways. By integrating it into bioactive peptides, researchers can modulate cellular functions such as signal transduction and metabolism. This application enables the elucidation of complex cellular processes and contributes to the advancement of biomedical research.

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