Nω-Methyl-L-arginine hydrochloride
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Nω-Methyl-L-arginine hydrochloride

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Category
L-Amino Acids
Catalog number
BAT-004160
CAS number
156706-47-7
Molecular Formula
C7H16N4O2·HCl
Molecular Weight
224.73
Nω-Methyl-L-arginine hydrochloride
IUPAC Name
(2S)-2-amino-5-[(N'-methylcarbamimidoyl)amino]pentanoic acid;hydrochloride
Synonyms
L-Arg(Me)-OH HCl; Nomega-Methyl-L-arginine hydrochloride
Appearance
White solid to thick paste
Purity
≥ 95% (HPLC)
Boiling Point
392.7°C
Storage
Store at 2-8 °C
InChI
InChI=1S/C7H16N4O2.ClH/c1-10-7(9)11-4-2-3-5(8)6(12)13;/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11);1H/t5-;/m0./s1
InChI Key
QYGXVJHXZUSLQC-JEDNCBNOSA-N
Canonical SMILES
CN=C(N)NCCCC(C(=O)O)N.Cl

Nω-Methyl-L-arginine hydrochloride, a potent nitric oxide synthase (NOS) inhibitor, serves as a valuable asset in various research pursuits. Here are the key applications:

Cardiovascular Research: Delving into the realm of cardiovascular research, Nω-Methyl-L-arginine hydrochloride is harnessed to probe the intricate role of nitric oxide in cardiovascular function and disease. By impeding NOS activity, scientists can scrutinize the repercussions of diminished nitric oxide on blood pressure, vascular tone, and cardiac performance. This exploration aids in unraveling the underlying mechanisms of hypertension and diverse cardiovascular maladies, shedding light on the complexities of cardiovascular health.

Neuroscience: In the realm of neuroscience, Nω-Methyl-L-arginine hydrochloride emerges as a pivotal tool for unraveling the involvement of nitric oxide in neural processes and signaling cascades. By inhibiting NOS, researchers can delve into the impacts on neuronal communication, synaptic plasticity, and neuroinflammatory responses. This quest contributes to the understanding of neurodegenerative disorders and neuropsychiatric conditions, offering insights into the intricate workings of the brain and its intricate mechanisms.

Inflammation Research: Stepping into the domain of inflammation research, Nω-Methyl-L-arginine hydrochloride finds its application in studying inflammatory responses, given the pivotal role of nitric oxide as a key mediator in inflammation pathways. Through NOS inhibition, researchers can observe alterations in inflammatory cytokines, immune cell dynamics, and tissue integrity. This critical data aids in the development of anti-inflammatory strategies and deepens our comprehension of the pathogenesis of inflammatory ailments, paving the way for novel therapeutic interventions.

Cancer Research: In the landscape of oncology, Nω-Methyl-L-arginine hydrochloride stands as a cornerstone for investigating the interplay between nitric oxide and tumor biology. Diminished nitric oxide levels engender impacts on tumor proliferation, angiogenesis, and metastatic potential, offering a lens into the intricate relationship between nitric oxide signaling and cancer progression. This compound serves as a conduit for comprehending the complexities of cancer biology, unraveling new avenues for potential therapeutic interventions in the fight against cancer.

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