1.Biogenetic origin of the D-isoleucine and N-methyl-L-alloisoleucine residues in the actinomycins.
Yajima T, Mason K, Katz E. Antimicrob Agents Chemother. 1976 Feb;9(2):224-32.
Studies with (14)C-labeled isoleucine stereisomers have established that l-alloisoleucine, d-alloisoleucine, and d-isoleucine may function as precursors for the biogenesis of d-isoleucine and N-methyl-l-alloisoleucine residues in actinomycin. l-[(14)C]isoleucine appears to be employed chiefly for d-alloisoleucine (and N-methylisoleucine [?] formation); however, its role in the biosynthesis of d-isoleucine and N-methylalloisoleucine remains unclear. The potential pathway of biosynthesis of d-isoleucine and N-methyl-l-isoleucine is discussed.
2.Natural enniatin A, a mixture of optical isomers containing both erythro- and threo-N-methyl-L-isoleucine residues.
Audhya TK, Russell DW. J Chem Soc Perkin 1. 1974;7:743-6.