N-ω-Nitro-L-arginine p-nitroanilide hydrobromide
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N-ω-Nitro-L-arginine p-nitroanilide hydrobromide

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Category
L-Amino Acids
Catalog number
BAT-006054
CAS number
29028-61-3
Molecular Formula
C12H18BrN7O5
Molecular Weight
420.22
N-ω-Nitro-L-arginine p-nitroanilide hydrobromide
IUPAC Name
(2S)-2-amino-5-[[amino(nitramido)methylidene]amino]-N-(4-nitrophenyl)pentanamide;hydrobromide
Synonyms
H-Arg(NO2)-pNA HBr
InChI
InChI=1S/C12H17N7O5.BrH/c13-10(2-1-7-15-12(14)17-19(23)24)11(20)16-8-3-5-9(6-4-8)18(21)22;/h3-6,10H,1-2,7,13H2,(H,16,20)(H3,14,15,17);1H/t10-;/m0./s1
InChI Key
VLIUCLVWDVXVTH-PPHPATTJSA-N
Canonical SMILES
C1=CC(=CC=C1NC(=O)C(CCCN=C(N)N[N+](=O)[O-])N)[N+](=O)[O-].Br

N-ω-Nitro-L-arginine p-nitroanilide hydrobromide, a specialized inhibitor of nitric oxide synthase, finds significant applications in bioscience research and medicine.

Neuroscience Research: Delving into neural signaling and brain function, N-ω-Nitro-L-arginine p-nitroanilide hydrobromide serves as a potent tool for studying the intricate role of nitric oxide. By inhibiting nitric oxide synthase, researchers embark on an exploration of how nitric oxide influences processes like synaptic plasticity, neuroinflammation, and neurodegeneration. The insights gleaned from these investigations promise to unravel the underlying mechanisms of various neurological disorders with unparalleled depth and complexity.

Cardiovascular Research: Positioned at the forefront of cardiovascular science, this compound is instrumental in unraveling the mysteries of nitric oxide’s impact on vascular function and blood pressure regulation. Through targeted inhibition of nitric oxide production, researchers illuminate its effects on vasodilation, endothelial function, and overall cardiovascular well-being. These comprehensive studies play a pivotal role in advancing our understanding of cardiovascular diseases and formulating innovative therapeutic approaches of unparalleled sophistication.

Inflammation Studies: In the domain of inflammation research, N-ω-Nitro-L-arginine p-nitroanilide hydrobromide emerges as a key player in investigating the intricate interplay of nitric oxide in inflammatory responses. By inhibiting nitric oxide synthase, researchers embark on a journey to dissect the impact of nitric oxide on immune cell functionality, cytokine release, and inflammation pathways. These profound investigations not only shed light on novel targets for anti-inflammatory therapies but also offer a nuanced understanding of the intricate mechanisms governing immune responses.

Cancer Research: In the realm of oncology, N-ω-Nitro-L-arginine p-nitroanilide hydrobromide assumes a pivotal role in unraveling the enigmatic role of nitric oxide in tumor progression and metastasis. By manipulating nitric oxide production, researchers unveil its profound effects on tumor growth, angiogenesis, and the complex tumor microenvironment. These deep insights serve as the foundation for pioneering strategies in cancer treatment, offering a sophisticated understanding of tumor biology with unparalleled intricacy and detail.

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