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N-Succinimidyl 6-Biotinamidohexanoate

* Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

Biotinamidohexanoic acid N-hydroxysuccinimide ester is an amine-reactive, activated form of biotin incorporating an aminocaproyl spacer (X) that can reduce the steric hindrance in binding avidin to some biotinylated compounds.

Category

Peptide Synthesis Reagents

Catalog number

BAT-008024

CAS number

72040-63-2

Molecular Formula

C20H30N4O6S

Molecular Weight

454.54

Specification

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoate

Synonyms

Biotin-X, succinimidyl ester ; Link-EZ NHS-LC-Biotin; Biotin-X, SE; Biotin-AC5-OSU; 2,5-Dioxopyrrolidin-1-yl 6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoate; Nhs-LC-biotin; Biotinamidohexanoic acid N-hydroxysuccinimide ester; Biotin-C5-NHS Ester; (+)-Biotin-LC-NHS Ester; BACHS; Succinimidyl-6-(biotinamido) Hexanoate; N-Succinimidyl 6-Biotinamidohexanoate; Biotin-X, succinimidyl ester; AK161916; Succinimidyl-6-biotinamide hexanoate; LC-NHS-(+)-Biotin

Appearance

White powder

Purity

≥ 97% (HPLC)

Density

1.350±0.10 g/cm3 (Predicted)

Melting Point

169-171 °C

Storage

-20 °C under inert atmosphere

Solubility

Slightly soluble in DMSO, Methanol (Heated)

InChI

InChI=1S/C20H30N4O6S/c25-15(7-4-3-6-14-19-13(12-31-14)22-20(29)23-19)21-11-5-1-2-8-18(28)30-24-16(26)9-10-17(24)27/h13-14,19H,1-12H2,(H,21,25)(H2,22,23,29)/t13-,14-,19-/m0/s1

InChI Key

UVGHPGOONBRLCX-NJSLBKSFSA-N

Canonical SMILES

C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3