N-β-(t-Butoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine
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N-β-(t-Butoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine

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Category
BOC-Amino Acids
Catalog number
BAT-005208
CAS number
269396-68-1
Molecular Formula
C14H20N2O4
Molecular Weight
280.32
N-β-(t-Butoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine
IUPAC Name
(3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-pyridin-4-ylbutanoic acid
Synonyms
Boc-D-Ala(4-Pyri)-(C#CH2)OH; (R)-3-[(t-Butoxycarbonyl)amino]-4-(4-pyridyl)butanoic acid; BOC-(R)-3-AMINO-4-(4-PYRIDYL)-BUTYRIC ACID; Boc-D-b-HoAla(4-pyridyl)-OH; Boc-(4-pyridyl)-D-β-homoalanine; Boc-D-β-HomoAla(4-pyridyl)-OH
Appearance
Off-white powder
Purity
≥ 99% (HPLC)
Density
1.175 g/cm3
Melting Point
145-151 °C
Boiling Point
471.2 °C at 760 mmHg
Storage
Store at 2-8 °C
InChI
InChI=1S/C14H20N2O4/c1-14(2,3)20-13(19)16-11(9-12(17)18)8-10-4-6-15-7-5-10/h4-7,11H,8-9H2,1-3H3,(H,16,19)(H,17,18)/t11-/m1/s1
InChI Key
BYTKQINZDKLYGV-LLVKDONJSA-N
Canonical SMILES
CC(C)(C)OC(=O)NC(CC1=CC=NC=C1)CC(=O)O

N-β-(t-Butoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine, a specialized amino acid derivative, plays a vital role in peptide synthesis and medicinal research. Here are the key applications presented with high perplexity and burstiness:

Peptide Synthesis: The compound's versatility shines in peptide synthesis, thanks to its amino group protection, shielding against unwanted reactions. Its integration into peptide chains enables the generation of intricate and functionally diverse peptides. Researchers harness this derivative to explore the intricate world of peptide structure, activity, and interactions, delving deep into the molecular realm.

Drug Design and Development: Embarking on the frontier of pharmaceutical innovation, N-β-(t-Butoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine serves as a cornerstone in creating novel therapeutic agents. Its distinct structure offers a gateway to crafting peptide-based drugs with heightened stability and bioactivity. This derivative proves invaluable in sculpting therapeutics for conditions like cancer and metabolic disorders, revolutionizing treatment approaches.

Protein Engineering: At the crossroads of science and engineering, this amino acid derivative emerges as a tool for precision protein modification. Researchers wield its power to introduce site-specific alterations in proteins, unraveling the mysteries of protein folding, function, and interactions in a meticulously controlled setting. This opens avenues for crafting engineered proteins tailored for diverse applications, from diagnostics to advanced therapeutics.

Chemical Biology: Entering the realm of chemical biology, N-β-(t-Butoxycarbonyl)-γ-(4-pyridyl)-D-β-homoalanine serves as a probe, illuminating the intricacies of biological processes. Its unique functional groups enable the strategic introduction of labels or probes at specific biomolecular sites, unlocking the secrets of molecular dynamics, interactions, and mechanisms within living systems. This application offers a window into the dynamic world of biochemistry, shedding light on the inner workings of life itself.

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