N-Boc-cis-4-Hydroxy-D-proline
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N-Boc-cis-4-Hydroxy-D-proline

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N-Boc-cis-4-Hydroxy-D-proline is a non-cleavable ADC linker and also an alkyl chain-based PROTAC linker.

Category
BOC-Amino Acids
Catalog number
BAT-003091
CAS number
135042-12-5
Molecular Formula
C10H17NO5
Molecular Weight
231.25
N-Boc-cis-4-Hydroxy-D-proline
IUPAC Name
(2R,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
Synonyms
Boc-D-cis-Hyp-OH; (2R,4R)-1-(t-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid; Boc-Cis-4-Hydroxy-D-Proline; Boc-(2R,4R)-(+)-4-hydroxypyrrolidine-2-carboxylic acid
Purity
≥ 98%
Density
1.312 g/cm3
Melting Point
145 °C
Boiling Point
390.9±42.0 °C
Storage
Store at 2-8 °C
InChI
InChI=1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7-/m1/s1
InChI Key
BENKAPCDIOILGV-RNFRBKRXSA-N
Canonical SMILES
CC(C)(C)OC(=O)N1CC(CC1C(=O)O)O
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