N-β-(t-Butoxycarbonyl)-N-β-methyl-β-alanine
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N-β-(t-Butoxycarbonyl)-N-β-methyl-β-alanine

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Category
BOC-Amino Acids
Catalog number
BAT-004783
CAS number
124072-61-3
Molecular Formula
C9H17NO4
Molecular Weight
203.23
N-β-(t-Butoxycarbonyl)-N-β-methyl-β-alanine
IUPAC Name
3-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]propanoic acid
Synonyms
Boc-β-MeAla-OH; Boc-MeGly-(C#CH2)OH; 3-[t-Butoxycarbonyl(methyl)amino]propanoic acid
Purity
95%
Density
1.113±0.06 g/cm3(Predicted)
Melting Point
59-62 ℃
Boiling Point
307.4±21.0 °C(Predicted)
Storage
Store at 2-8°C
InChI
InChI=1S/C9H17NO4/c1-9(2,3)14-8(13)10(4)6-5-7(11)12/h5-6H2,1-4H3,(H,11,12)
InChI Key
BBIFRGBXCKOUBW-UHFFFAOYSA-N
Canonical SMILES
CC(C)(C)OC(=O)N(C)CCC(=O)O

N-β-(t-Butoxycarbonyl)-N-β-methyl-β-alanine, a specialized chemical compound, finds diverse applications in biochemistry and pharmaceutical research. Here are the key applications expressed with high perplexity and burstiness:

Peptide Synthesis: Acting as a fundamental unit in solid-phase peptide synthesis, N-β-(t-Butoxycarbonyl)-N-β-methyl-β-alanine plays a crucial role. Its incorporation into peptide sequences provides shielding to functional groups, ensuring the meticulous construction of intricate peptides. This process is imperative for crafting ultrapure peptides, essential for both biochemical investigations and therapeutic endeavors.

Medicinal Chemistry: Within the realm of medicinal chemistry, this compound acts as a pivotal stepping stone in the creation of various pharmacologically active compounds. By integrating it into drug structures, researchers can tailor pharmacokinetic properties like solubility and stability. This optimization aids in the development of groundbreaking pharmaceuticals with heightened efficacy and mitigated adverse effects.

Bioconjugation: N-β-(t-Butoxycarbonyl)-N-β-methyl-β-alanine finds utility in bioconjugation methodologies, facilitating the linkage of peptides to diverse molecules, including drugs and imaging agents. This binding process is critical for fabricating targeted therapeutics and diagnostic tools adept at precise interactions with biological targets. The compound's robust stability and reactivity render it an invaluable asset in sophisticated bioconjugation schemes.

Protein Engineering: Enlisted in the domain of protein engineering, this compound is harnessed to introduce precise alterations into protein frameworks. Through its integration into proteins, scientists can delve into the repercussions of specific amino acid substitutions on protein functionality and robustness. This profound understanding is pivotal for tailoring proteins with heightened attributes suitable for both industrial applications and therapeutic interventions.

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