Neuropeptide SF (mouse, rat) acetate
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Neuropeptide SF (mouse, rat) acetate

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Neuropeptide SF (mouse, rat) acetate is a neuropeptide FF receptor agonist (Ki = 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). NPSF may play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH.

Category
Peptide Inhibitors
Catalog number
BAT-016339
CAS number
2760881-61-4
Molecular Formula
C42H69N13O12
Molecular Weight
948.08
Neuropeptide SF (mouse, rat) acetate
IUPAC Name
acetic acid;(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
Synonyms
H-Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2.CH3CO2H; L-seryl-L-leucyl-L-alanyl-L-alanyl-L-prolyl-L-glutaminyl-L-arginyl-L-phenylalaninamide acetic acid
Related CAS
230960-31-3 (free base)
Purity
≥95%
Sequence
SLAAPQRF-NH2.CH3CO2H
Storage
Store at -20°C
InChI
InChI=1S/C40H65N13O10.C2H4O2/c1-21(2)18-29(52-34(58)25(41)20-54)37(61)47-22(3)33(57)48-23(4)39(63)53-17-9-13-30(53)38(62)50-27(14-15-31(42)55)36(60)49-26(12-8-16-46-40(44)45)35(59)51-28(32(43)56)19-24-10-6-5-7-11-24;1-2(3)4/h5-7,10-11,21-23,25-30,54H,8-9,12-20,41H2,1-4H3,(H2,42,55)(H2,43,56)(H,47,61)(H,48,57)(H,49,60)(H,50,62)(H,51,59)(H,52,58)(H4,44,45,46);1H3,(H,3,4)/t22-,23-,25-,26-,27-,28-,29-,30-;/m0./s1
InChI Key
IHKLLBKUWFKFHD-JQRMDQEZSA-N
Canonical SMILES
CC(C)CC(C(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(CCC(=O)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CC2=CC=CC=C2)C(=O)N)NC(=O)C(CO)N.CC(=O)O
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