Nma-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2
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Nma-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2

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Nma-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2 is a quenched fluorogenic peptide substrate containing the C-terminal β-APP (amyloid β-peptide precursor protein) amino acid sequence which is cleaved by γ-secretase. It can be used in the assays of γ-secretase activity.

Category
Functional Peptides
Catalog number
BAT-016763
CAS number
600728-90-3
Molecular Formula
C70H116N26O18
Molecular Weight
1609.83
Nma-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(Dnp)-D-Arg-D-Arg-D-Arg-NH2
Synonyms
[2-(Methylamino)benzoyl]glycylglycyl-L-valyl-L-valyl-L-isoleucyl-L-alanyl-L-threonyl-L-valyl-[Nε-(2,4-dinitrophenyl)-L-lysyl]-D-arginyl-D-arginyl-D-arginine amide; N-Me-Abz-Amyloid β; A4 Protein Precursor770 (708-715)-Lys(Dnp)-D-Arg-D-Arg-D-Arg amide
Sequence
NMA-GGVVIATVK(DNP)-DRDRDR-NH2
Storage
Store at -20 °C
Solubility
Soluble in DMSO.
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